Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 3
LIF
 87.5 72
RA2159 IKK16 2.0
uM
 3
LIF
 107.0 51
RA2159 JNK-IN-8 3.0
uM
 3
LIF
 96.0 59
N2586 3
LIF
 129.5 62
N2586 PD184352 0.1
uM
 3
LIF
 158.0 79
N2586 Lestaurtinib 0.3
uM
 3
LIF
 113.0 63
N2586 Ruxolitinib 0.3
uM
 3
LIF
 351.0 56
N2586 Tofacitinib 0.3
uM
 3
LIF
 196.5 62
N2586 IKK16 2.0
uM
 3
LIF
 109.0 79
N2586 JNK-IN-8 3.0
uM
 3
LIF
 123.0 65
RA2159 IL-17A 100
ng/mL
 3
LIF
 115.0 54
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
LIF
 91.0 74
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
LIF
 97.0 60
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
LIF
 80.0 55
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
LIF
 75.0 53
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
LIF
 77.5 68
N2586 IL-17A 100
ng/mL
 3
LIF
 147.0 61
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
LIF
 136.0 67
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
LIF
 127.5 60
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
LIF
 330.0 46
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
LIF
 119.0 50
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
LIF
 115.5 52
RA2159 IL-6 100
ug/mL
 3
LIF
 84.0 51
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
LIF
 90.0 50
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
LIF
 77.0 49