Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-11 0.3
uM
IL-17A 100
ng/mL
4
IL-12 (p70)
73.0 73
N2586 Tofacitinib 0.3
uM
4
IL-12 (p70)
43.0 65
RA2159 IL-6 100
ug/mL
4
IL-12 (p70)
53.0 52
RA2159 EO1428 1.0
uM
IL-6 100
ug/mL
4
IL-12 (p70)
42.0 71
RA2159 PI103 0.1
uM
IL-6 100
ug/mL
4
IL-12 (p70)
42.5 38
RA2159 Sigma A6730 3.0
uM
IL-6 100
ug/mL
4
IL-12 (p70)
59.5 46
RA2159 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
4
IL-12 (p70)
49.0 63
RA2159 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
4
IL-12 (p70)
49.0 55
RA2159 Ruxolitinib 0.3
uM
4
IL-12 (p70)
56.5 38
N2586 IL-6 100
ug/mL
4
IL-12 (p70)
67.0 50
N2586 EO1428 1.0
uM
IL-6 100
ug/mL
4
IL-12 (p70)
78.0 49
N2586 PI103 0.1
uM
IL-6 100
ug/mL
4
IL-12 (p70)
69.0 38
N2586 Sigma A6730 3.0
uM
IL-6 100
ug/mL
4
IL-12 (p70)
75.0 50
N2586 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
4
IL-12 (p70)
64.0 65
N2586 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
4
IL-12 (p70)
37.5 52
N2586 Ruxolitinib 0.3
uM
4
IL-12 (p70)
78.0 63
RA2159 IL-1 alpha 100
ng/mL
4
IL-12 (p70)
78.0 51
RA2159 EO1428 1.0
uM
IL-1 alpha 100
ng/mL
4
IL-12 (p70)
53.0 71
RA2159 PI103 0.1
uM
IL-1 alpha 100
ng/mL
4
IL-12 (p70)
74.5 66
RA2159 Sigma A6730 3.0
uM
IL-1 alpha 100
ng/mL
4
IL-12 (p70)
75.0 55
RA2159 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
4
IL-12 (p70)
70.0 49
RA2159 JNK-IN-11 0.3
uM
IL-1 alpha 100
ng/mL
4
IL-12 (p70)
69.0 77
RA2159 Lestaurtinib 0.3
uM
4
IL-12 (p70)
53.0 57
N2586 IL-1 alpha 100
ng/mL
4
IL-12 (p70)
105.0 79
N2586 EO1428 1.0
uM
IL-1 alpha 100
ng/mL
4
IL-12 (p70)
90.5 50