Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 54.5 | 66 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 26.5 | 76 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 64.5 | 64 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 57.0 | 81 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 53.0 | 69 | |
| N2586 | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 78.5 | 94 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 59.5 | 68 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 42.5 | 48 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 71.5 | 68 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 89.5 | 64 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL-12 (p70) | 81.5 | 70 | |
| RA2159 | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 51.5 | 70 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 68.0 | 69 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 56.0 | 71 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 54.0 | 58 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 49.0 | 73 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 47.5 | 74 | |
| N2586 | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 83.0 | 72 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 75.5 | 74 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 55.5 | 68 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 92.5 | 62 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 100.0 | 71 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL-12 (p70) | 86.0 | 61 | |
| RA2159 | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 52.5 | 68 | ||||
| RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | IL-12 (p70) | 47.0 | 63 |