Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Lestaurtinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 12.0 63
N2586 Ruxolitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 15.5 32
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 18.5 52
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1B
 16.0 37
0
IL-1B
 20.5 48
RA2159 2
IL-1B
 18.5 50
RA2159 EO1428 1.0
uM
 2
IL-1B
 21.5 84
RA2159 PI103 0.1
uM
 2
IL-1B
 115.0 57
RA2159 Sigma A6730 3.0
uM
 2
IL-1B
 19.0 64
RA2159 JNK-IN-8 3.0
uM
 2
IL-1B
 18.5 62
RA2159 JNK-IN-11 0.3
uM
 2
IL-1B
 17.5 66
RA2159 2
IL-1B
 17.0 45
N2586 2
IL-1B
 18.0 42
N2586 EO1428 1.0
uM
 2
IL-1B
 16.0 55
N2586 PI103 0.1
uM
 2
IL-1B
 16.5 60
N2586 Sigma A6730 3.0
uM
 2
IL-1B
 13.0 49
N2586 JNK-IN-8 3.0
uM
 2
IL-1B
 16.0 55
N2586 JNK-IN-11 0.3
uM
 2
IL-1B
 15.0 50
N2586 2
IL-1B
 17.0 53
0
IL-1B
 17.0 47
0
IL-1B
 17.0 31
RA2159 TNF-a 100
ng/mL
 2
IL-1B
 47.0 69
RA2159 EO1428 1.0
uM
 TNF-a 100
ng/mL
 2
IL-1B
 51.0 71
RA2159 PI103 0.1
uM
 TNF-a 100
ng/mL
 2
IL-1B
 49.0 51
RA2159 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 2
IL-1B
 47.0 52