Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Ruxolitinib | 0.3 | uM | 1 | IL-1B | 13.0 | 72 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | IL-1B | 15.0 | 66 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IL-1B | 15.5 | 68 | ||||
| N2586 | 1 | IL-1B | 16.0 | 56 | |||||||
| RA2159 | Visfatin | 1 | ng/mL | 1 | IL-1B | 14.0 | 51 | ||||
| RA2159 | PD184352 | 0.1 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 16.0 | 67 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 13.0 | 81 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 17.0 | 68 | |
| RA2159 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 14.0 | 45 | |
| RA2159 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 14.0 | 62 | |
| N2586 | Visfatin | 1 | ng/mL | 1 | IL-1B | 13.0 | 62 | ||||
| N2586 | PD184352 | 0.1 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 33.0 | 53 | |
| N2586 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 14.0 | 64 | |
| N2586 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 15.0 | 56 | |
| N2586 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 13.0 | 50 | |
| N2586 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 1 | IL-1B | 11.0 | 33 | |
| 0 | IL-1B | 14.0 | 57 | ||||||||
| RA2159 | Poly(I:C) | 2 | ug/mL | 1 | IL-1B | 33.0 | 63 | ||||
| RA2159 | PD184352 | 0.1 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-1B | 36.0 | 47 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-1B | 40.0 | 50 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-1B | 19.0 | 47 | |
| RA2159 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-1B | 18.0 | 59 | |
| RA2159 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-1B | 14.0 | 67 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | IL-1B | 28.0 | 30 | ||||
| N2586 | PD184352 | 0.1 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-1B | 21.0 | 57 |