Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
SCF
 39.5 68
RA2159 IKK16 2.0
uM
 IGF-I 100
ug/mL
 3
SCF
 38.0 73
RA2159 3
SCF
 37.0 81
N2586 IGF-I 100
ug/mL
 3
SCF
 85.0 73
N2586 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
SCF
 80.5 66
N2586 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
SCF
 59.0 82
N2586 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
SCF
 77.0 73
N2586 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
SCF
 53.0 75
N2586 IKK16 2.0
uM
 IGF-I 100
ug/mL
 3
SCF
 49.5 68
N2586 3
SCF
 75.0 78
RA2159 EGF 100
ng/mL
 3
SCF
 39.0 81
RA2159 PD184352 0.1
uM
 EGF 100
ng/mL
 3
SCF
 39.0 69
RA2159 Lestaurtinib 0.3
uM
 EGF 100
ng/mL
 3
SCF
 31.0 79
RA2159 Ruxolitinib 0.3
uM
 EGF 100
ng/mL
 3
SCF
 47.0 65
RA2159 Tofacitinib 0.3
uM
 EGF 100
ng/mL
 3
SCF
 41.0 82
RA2159 IKK16 2.0
uM
 EGF 100
ng/mL
 3
SCF
 40.0 79
RA2159 JNK-IN-11 0.3
uM
 3
SCF
 37.0 73
N2586 EGF 100
ng/mL
 3
SCF
 83.0 82
N2586 PD184352 0.1
uM
 EGF 100
ng/mL
 3
SCF
 83.0 63
N2586 Lestaurtinib 0.3
uM
 EGF 100
ng/mL
 3
SCF
 66.0 69
N2586 Ruxolitinib 0.3
uM
 EGF 100
ng/mL
 3
SCF
 91.0 66
N2586 Tofacitinib 0.3
uM
 EGF 100
ng/mL
 3
SCF
 53.0 70
N2586 IKK16 2.0
uM
 EGF 100
ng/mL
 3
SCF
 56.0 60
N2586 JNK-IN-11 0.3
uM
 3
SCF
 41.0 57
RA2159 3
SCF
 36.0 91