Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Ruxolitinib 0.3
uM
 Leptin 1
ng/mL
 3
SCF
 35.0 69
RA2159 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 3
SCF
 32.5 74
RA2159 IKK16 2.0
uM
 Leptin 1
ng/mL
 3
SCF
 41.0 75
N2586 Leptin 1
ng/mL
 3
SCF
 71.0 55
N2586 PD184352 0.1
uM
 Leptin 1
ng/mL
 3
SCF
 72.5 100
N2586 Lestaurtinib 0.3
uM
 Leptin 1
ng/mL
 3
SCF
 57.0 71
N2586 Ruxolitinib 0.3
uM
 Leptin 1
ng/mL
 3
SCF
 70.0 63
N2586 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 3
SCF
 57.5 76
N2586 IKK16 2.0
uM
 Leptin 1
ng/mL
 3
SCF
 62.0 85
RA2159 Adiponectin 5
ng/mL
 3
SCF
 65.5 72
RA2159 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
SCF
 56.0 73
RA2159 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
SCF
 56.0 82
RA2159 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
SCF
 56.0 68
RA2159 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
SCF
 62.0 65
RA2159 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
SCF
 60.0 76
N2586 Adiponectin 5
ng/mL
 3
SCF
 97.5 68
N2586 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
SCF
 96.5 68
N2586 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
SCF
 84.5 62
N2586 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
SCF
 98.0 57
N2586 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
SCF
 83.0 49
N2586 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
SCF
 84.0 90
RA2159 IGF-I 100
ug/mL
 3
SCF
 36.0 70
RA2159 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
SCF
 36.0 69
RA2159 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
SCF
 33.0 74
RA2159 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
SCF
 34.0 73