Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
SCF
32.0 87
N2586 Poly(I:C) 2
ug/mL
1
SCF
79.5 58
N2586 PD184352 0.1
uM
Poly(I:C) 2
ug/mL
1
SCF
83.5 46
N2586 Lestaurtinib 0.3
uM
Poly(I:C) 2
ug/mL
1
SCF
63.0 45
N2586 Ruxolitinib 0.3
uM
Poly(I:C) 2
ug/mL
1
SCF
87.0 55
N2586 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
1
SCF
73.0 39
N2586 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
1
SCF
74.5 36
0
SCF
27.0 63
RA2159 2
SCF
39.0 61
RA2159 EO1428 1.0
uM
2
SCF
43.0 72
RA2159 PI103 0.1
uM
2
SCF
44.0 67
RA2159 Sigma A6730 3.0
uM
2
SCF
44.0 82
RA2159 JNK-IN-8 3.0
uM
2
SCF
44.0 76
RA2159 JNK-IN-11 0.3
uM
2
SCF
46.5 72
RA2159 2
SCF
43.0 75
N2586 2
SCF
65.5 60
N2586 EO1428 1.0
uM
2
SCF
64.0 53
N2586 PI103 0.1
uM
2
SCF
63.0 67
N2586 Sigma A6730 3.0
uM
2
SCF
68.0 58
N2586 JNK-IN-8 3.0
uM
2
SCF
57.0 66
N2586 JNK-IN-11 0.3
uM
2
SCF
61.0 44
N2586 2
SCF
75.0 73
0
SCF
23.5 70
0
SCF
21.5 52
RA2159 TNF-a 100
ng/mL
2
SCF
93.0 90