Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
TNFb
 42.5 34
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
TNFb
 49.0 38
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
TNFb
 52.0 51
N2586 Sigma A6730 3.0
uM
 1
TNFb
 47.0 44
RA2159 IL-17A 100
ng/mL
 1
TNFb
 50.0 62
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
TNFb
 44.0 66
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
TNFb
 37.0 52
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
TNFb
 36.0 63
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
TNFb
 37.0 60
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
TNFb
 49.0 70
N2586 IL-17A 100
ng/mL
 1
TNFb
 51.0 37
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 1
TNFb
 51.0 37
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 1
TNFb
 94.0 28
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
TNFb
 55.0 31
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
TNFb
 44.0 35
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
TNFb
 56.5 60
RA2159 1
TNFb
 44.0 55
RA2159 PD184352 0.1
uM
 1
TNFb
 104.0 69
RA2159 Lestaurtinib 0.3
uM
 1
TNFb
 59.0 51
RA2159 Ruxolitinib 0.3
uM
 1
TNFb
 45.0 60
RA2159 Tofacitinib 0.3
uM
 1
TNFb
 43.0 57
RA2159 IKK16 2.0
uM
 1
TNFb
 40.0 50
RA2159 JNK-IN-8 3.0
uM
 1
TNFb
 44.0 43
N2586 1
TNFb
 38.0 63
N2586 PD184352 0.1
uM
 1
TNFb
 44.0 54