Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 EO1428 1.0
uM
 1
TNFb
 49.0 70
RA2159 IL-1 alpha 100
ng/mL
 1
TNFb
 91.0 52
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 85.0 64
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 61.0 45
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 79.0 57
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 57.0 50
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 63.0 59
RA2159 PI103 0.1
uM
 1
TNFb
 43.5 38
N2586 IL-1 alpha 100
ng/mL
 1
TNFb
 72.5 62
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 66.0 56
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 68.5 50
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 76.0 51
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 72.0 45
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TNFb
 62.5 52
N2586 PI103 0.1
uM
 1
TNFb
 48.0 37
RA2159 IL-6 100
ug/mL
 1
TNFb
 62.0 56
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
TNFb
 51.0 65
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
TNFb
 49.5 48
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
TNFb
 49.0 59
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
TNFb
 47.0 66
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
TNFb
 36.0 39
RA2159 Sigma A6730 3.0
uM
 1
TNFb
 41.5 50
N2586 IL-6 100
ug/mL
 1
TNFb
 50.5 56
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
TNFb
 45.5 52
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
TNFb
 38.0 60