Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IL-6 | 100 | ug/mL | 0 | IL-6 | 36245.0 | 57 | |||||
| IL-6 | 100 | ug/mL | 0 | IL-6 | 35720.0 | 55 | |||||
| IL-6 | 100 | ug/mL | 0 | IL-6 | 35706.5 | 88 | |||||
| IL-6 | 100 | ug/mL | 0 | IL-6 | 35342.0 | 66 | |||||
| N2586 | Sigma A6730 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 2 | IL-6 | 33374.0 | 63 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-6 | 32595.5 | 74 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 32527.0 | 72 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 32328.0 | 63 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-6 | 31957.0 | 69 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 3 | IL-6 | 31911.0 | 79 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 3 | IL-6 | 31911.0 | 61 | ||||
| RA2159 | Sigma A6730 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 31808.5 | 64 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 31782.0 | 49 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 31713.5 | 68 | |
| N2586 | PI103 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 2 | IL-6 | 31645.0 | 73 | |
| RA2159 | Sigma A6730 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 2 | IL-6 | 31372.5 | 56 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-6 | 31329.5 | 78 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-6 | 31181.0 | 56 | |
| RA2159 | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 31181.0 | 33 | ||||
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-6 | 31145.0 | 72 | |
| RA2159 | PI103 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 30953.0 | 52 | |
| RA2159 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 30885.0 | 49 | |
| N2586 | Sigma A6730 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 30200.0 | 47 | |
| RA2159 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 2 | IL-6 | 30075.5 | 52 | |
| N2586 | EO1428 | 1.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-6 | 29961.0 | 52 |