Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 61.5 | 72 | |
| N2586 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 58.0 | 33 | |
| RA2159 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 63.0 | 43 | |
| N2586 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 60.0 | 57 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 59.0 | 49 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 61.5 | 70 | |
| RA2159 | Visfatin | 1 | ng/mL | 1 | MIP-1B | 67.5 | 68 | ||||
| RA2159 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 64.5 | 74 | |
| N2586 | Visfatin | 1 | ng/mL | 1 | MIP-1B | 58.0 | 76 | ||||
| N2586 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 61.0 | 71 | |
| N2586 | Leptin | 1 | ng/mL | 1 | MIP-1B | 62.0 | 49 | ||||
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 72.0 | 59 | |
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 63.0 | 40 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 61.0 | 88 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 64.0 | 67 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 63.0 | 48 | |
| RA2159 | PD184352 | 0.1 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 64.0 | 69 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 74.5 | 70 | |
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 69.0 | 61 | |
| RA2159 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 62.5 | 78 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | MIP-1B | 69.0 | 79 | ||||
| N2586 | PD184352 | 0.1 | uM | Visfatin | 1 | ng/mL | 1 | MIP-1B | 64.0 | 59 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 64.0 | 59 | |
| RA2159 | Leptin | 1 | ng/mL | 2 | MIP-1B | 60.0 | 82 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | MIP-1B | 60.0 | 61 |