Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IL-17A 100
ng/mL
 2
IL-12 (p70)
 86.0 57
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL-12 (p70)
 53.0 68
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL-12 (p70)
 52.0 59
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL-12 (p70)
 53.5 70
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IL-12 (p70)
 49.0 55
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IL-12 (p70)
 47.0 73
N2586 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 51.0 50
RA2159 2
IL-12 (p70)
 41.0 61
RA2159 EO1428 1.0
uM
 2
IL-12 (p70)
 37.0 73
RA2159 PI103 0.1
uM
 2
IL-12 (p70)
 36.0 72
RA2159 Sigma A6730 3.0
uM
 2
IL-12 (p70)
 33.5 40
RA2159 JNK-IN-8 3.0
uM
 2
IL-12 (p70)
 30.0 54
RA2159 JNK-IN-11 0.3
uM
 2
IL-12 (p70)
 34.5 70
RA2159 IKK16 2.0
uM
 2
IL-12 (p70)
 32.0 30
N2586 2
IL-12 (p70)
 54.5 54
N2586 EO1428 1.0
uM
 2
IL-12 (p70)
 50.0 63
N2586 PI103 0.1
uM
 2
IL-12 (p70)
 44.0 69
N2586 Sigma A6730 3.0
uM
 2
IL-12 (p70)
 42.5 64
N2586 JNK-IN-8 3.0
uM
 2
IL-12 (p70)
 51.0 61
N2586 JNK-IN-11 0.3
uM
 2
IL-12 (p70)
 40.0 55
N2586 IKK16 2.0
uM
 2
IL-12 (p70)
 46.0 45
RA2159 EGF 100
ng/mL
 2
IL-12 (p70)
 29.0 95
RA2159 EO1428 1.0
uM
 EGF 100
ng/mL
 2
IL-12 (p70)
 37.0 71
RA2159 PI103 0.1
uM
 EGF 100
ng/mL
 2
IL-12 (p70)
 32.0 60
RA2159 Sigma A6730 3.0
uM
 EGF 100
ng/mL
 2
IL-12 (p70)
 29.0 57