Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
IL-6 100
ug/mL
 0
IL-7
 7.0 49
IL-17A 100
ng/mL
 0
IL-7
 15.0 69
EGF 100
ng/mL
 0
IL-7
 9.0 58
IGF-I 100
ug/mL
 0
IL-7
 8.0 79
Adiponectin 5
ng/mL
 0
IL-7
 50.5 62
Leptin 1
ng/mL
 0
IL-7
 7.5 70
Visfatin 1
ng/mL
 0
IL-7
 10.0 36
Poly(I:C) 2
ug/mL
 0
IL-7
 8.0 65
0
IL-12 (p70)
 14.0 59
RA2159 1
IL-12 (p70)
 47.0 74
RA2159 PD184352 0.1
uM
 1
IL-12 (p70)
 44.0 59
RA2159 Lestaurtinib 0.3
uM
 1
IL-12 (p70)
 66.0 69
RA2159 Ruxolitinib 0.3
uM
 1
IL-12 (p70)
 51.0 81
RA2159 Tofacitinib 0.3
uM
 1
IL-12 (p70)
 41.0 70
RA2159 IKK16 2.0
uM
 1
IL-12 (p70)
 45.5 74
RA2159 1
IL-12 (p70)
 44.0 51
N2586 1
IL-12 (p70)
 56.0 68
N2586 PD184352 0.1
uM
 1
IL-12 (p70)
 64.0 77
N2586 Lestaurtinib 0.3
uM
 1
IL-12 (p70)
 72.0 51
N2586 Ruxolitinib 0.3
uM
 1
IL-12 (p70)
 62.0 69
N2586 Tofacitinib 0.3
uM
 1
IL-12 (p70)
 54.0 63
N2586 IKK16 2.0
uM
 1
IL-12 (p70)
 56.0 49
N2586 1
IL-12 (p70)
 55.0 35
0
IL-12 (p70)
 15.5 60
0
IL-12 (p70)
 16.0 49