Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 56.0 | 57 | ||||
| RA2159 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 48.0 | 73 | |
| RA2159 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 48.0 | 64 | |
| RA2159 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 50.0 | 83 | |
| RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 60.5 | 48 | |
| RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 52.0 | 65 | |
| RA2159 | EO1428 | 1.0 | uM | 1 | IL-12 (p70) | 34.5 | 66 | ||||
| N2586 | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 85.0 | 64 | ||||
| N2586 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 73.0 | 73 | |
| N2586 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 73.0 | 56 | |
| N2586 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 81.0 | 59 | |
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 59.5 | 60 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | IL-12 (p70) | 70.0 | 65 | |
| N2586 | EO1428 | 1.0 | uM | 1 | IL-12 (p70) | 70.0 | 30 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 60.0 | 64 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 58.0 | 77 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 38.0 | 65 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 74.5 | 64 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 71.0 | 74 | |
| RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 52.0 | 60 | |
| RA2159 | PI103 | 0.1 | uM | 1 | IL-12 (p70) | 44.0 | 74 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 79.5 | 56 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 71.5 | 66 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 64.5 | 54 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-12 (p70) | 82.0 | 51 |