Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-12 (p70) | 73.5 | 54 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-12 (p70) | 58.0 | 85 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-12 (p70) | 56.0 | 62 | |
| N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL-12 (p70) | 56.0 | 81 | |
| RA2159 | 1 | IL-12 (p70) | 52.0 | 51 | |||||||
| RA2159 | PD184352 | 0.1 | uM | 1 | IL-12 (p70) | 38.0 | 67 | ||||
| RA2159 | Lestaurtinib | 0.3 | uM | 1 | IL-12 (p70) | 53.0 | 75 | ||||
| RA2159 | Ruxolitinib | 0.3 | uM | 1 | IL-12 (p70) | 47.0 | 59 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 55.0 | 47 | ||||
| RA2159 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 39.0 | 81 | ||||
| RA2159 | JNK-IN-8 | 3.0 | uM | 1 | IL-12 (p70) | 52.5 | 56 | ||||
| N2586 | 1 | IL-12 (p70) | 53.0 | 74 | |||||||
| N2586 | PD184352 | 0.1 | uM | 1 | IL-12 (p70) | 62.0 | 57 | ||||
| N2586 | Lestaurtinib | 0.3 | uM | 1 | IL-12 (p70) | 67.0 | 35 | ||||
| N2586 | Ruxolitinib | 0.3 | uM | 1 | IL-12 (p70) | 56.0 | 61 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 70.0 | 45 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 82.0 | 60 | ||||
| N2586 | JNK-IN-8 | 3.0 | uM | 1 | IL-12 (p70) | 63.5 | 76 | ||||
| RA2159 | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 52.0 | 68 | ||||
| RA2159 | PD184352 | 0.1 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 53.5 | 64 | |
| RA2159 | Lestaurtinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 46.0 | 66 | |
| RA2159 | Ruxolitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 38.0 | 73 | |
| RA2159 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 57.0 | 78 | |
| RA2159 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 44.0 | 67 | |
| RA2159 | JNK-IN-11 | 0.3 | uM | 1 | IL-12 (p70) | 42.0 | 89 |