Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 63.0 | 84 | ||||
| N2586 | PD184352 | 0.1 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 77.5 | 58 | |
| N2586 | Lestaurtinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 56.5 | 42 | |
| N2586 | Ruxolitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 62.0 | 37 | |
| N2586 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 63.0 | 56 | |
| N2586 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 1 | IL-12 (p70) | 80.0 | 36 | |
| N2586 | JNK-IN-11 | 0.3 | uM | 1 | IL-12 (p70) | 58.0 | 80 | ||||
| RA2159 | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 48.0 | 59 | ||||
| RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 44.0 | 79 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 55.0 | 59 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 50.0 | 65 | |
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 43.0 | 91 | |
| RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 40.0 | 50 | |
| RA2159 | 1 | IL-12 (p70) | 41.0 | 55 | |||||||
| N2586 | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 56.0 | 39 | ||||
| N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 70.0 | 62 | |
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 66.5 | 72 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 68.5 | 48 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 48.0 | 51 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-12 (p70) | 61.5 | 70 | |
| N2586 | 1 | IL-12 (p70) | 63.0 | 72 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 39.0 | 77 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 31.0 | 73 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 35.5 | 50 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-12 (p70) | 38.0 | 58 |