Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL3
 49.0 61
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL3
 51.5 72
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL3
 66.0 61
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IL3
 40.0 69
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IL3
 40.5 52
RA2159 Tofacitinib 0.3
uM
 2
IL3
 42.0 38
N2586 IL-17A 100
ng/mL
 2
IL3
 43.0 52
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL3
 49.0 70
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL3
 52.0 11
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL3
 47.0 29
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IL3
 51.0 53
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IL3
 63.0 78
N2586 Tofacitinib 0.3
uM
 2
IL3
 52.0 76
RA2159 2
IL3
 42.0 78
RA2159 EO1428 1.0
uM
 2
IL3
 40.5 62
RA2159 PI103 0.1
uM
 2
IL3
 55.0 47
RA2159 Sigma A6730 3.0
uM
 2
IL3
 46.0 73
RA2159 JNK-IN-8 3.0
uM
 2
IL3
 47.0 61
RA2159 JNK-IN-11 0.3
uM
 2
IL3
 43.5 64
RA2159 IKK16 2.0
uM
 2
IL3
 97.5 86
N2586 2
IL3
 50.0 65
N2586 EO1428 1.0
uM
 2
IL3
 45.0 62
N2586 PI103 0.1
uM
 2
IL3
 40.0 77
N2586 Sigma A6730 3.0
uM
 2
IL3
 58.0 69
N2586 JNK-IN-8 3.0
uM
 2
IL3
 53.0 59