Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
M-CSF
 245.0 78
N2586 EO1428 1.0
uM
 3
M-CSF
 242.0 63
0
M-CSF
 68.0 46
RA2159 3
M-CSF
 91.0 63
RA2159 PD184352 0.1
uM
 3
M-CSF
 96.0 51
RA2159 Lestaurtinib 0.3
uM
 3
M-CSF
 119.5 58
RA2159 Ruxolitinib 0.3
uM
 3
M-CSF
 112.0 49
RA2159 Tofacitinib 0.3
uM
 3
M-CSF
 106.0 53
RA2159 IKK16 2.0
uM
 3
M-CSF
 105.0 55
RA2159 3
M-CSF
 172.0 72
N2586 3
M-CSF
 182.0 64
N2586 PD184352 0.1
uM
 3
M-CSF
 127.0 55
N2586 Lestaurtinib 0.3
uM
 3
M-CSF
 118.5 46
N2586 Ruxolitinib 0.3
uM
 3
M-CSF
 147.0 73
N2586 Tofacitinib 0.3
uM
 3
M-CSF
 122.0 48
N2586 IKK16 2.0
uM
 3
M-CSF
 120.5 40
N2586 3
M-CSF
 151.0 59
0
M-CSF
 53.5 58
RA2159 Poly(I:C) 2
ug/mL
 4
M-CSF
 185.0 73
RA2159 EO1428 1.0
uM
 Poly(I:C) 2
ug/mL
 4
M-CSF
 236.5 68
RA2159 PI103 0.1
uM
 Poly(I:C) 2
ug/mL
 4
M-CSF
 199.0 61
RA2159 Sigma A6730 3.0
uM
 Poly(I:C) 2
ug/mL
 4
M-CSF
 189.0 64
RA2159 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 4
M-CSF
 145.0 53
RA2159 JNK-IN-11 0.3
uM
 Poly(I:C) 2
ug/mL
 4
M-CSF
 157.0 65
N2586 Poly(I:C) 2
ug/mL
 4
M-CSF
 265.0 72