Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Ruxolitinib 0.3
uM
 1
b-NGF
 49.0 57
RA2159 Tofacitinib 0.3
uM
 1
b-NGF
 49.5 54
RA2159 IKK16 2.0
uM
 1
b-NGF
 40.0 53
RA2159 1
b-NGF
 49.0 82
N2586 1
b-NGF
 92.0 71
N2586 PD184352 0.1
uM
 1
b-NGF
 113.0 71
N2586 Lestaurtinib 0.3
uM
 1
b-NGF
 90.0 69
N2586 Ruxolitinib 0.3
uM
 1
b-NGF
 114.0 55
N2586 Tofacitinib 0.3
uM
 1
b-NGF
 94.5 38
N2586 IKK16 2.0
uM
 1
b-NGF
 72.0 41
N2586 1
b-NGF
 74.0 37
0
b-NGF
 8.5 58
0
b-NGF
 11.0 40
RA2159 TNF-a 100
ng/mL
 1
b-NGF
 168.5 58
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
b-NGF
 188.0 69
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 126.0 75
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 159.0 62
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 201.5 56
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
b-NGF
 62.0 61
RA2159 EO1428 1.0
uM
 1
b-NGF
 46.0 44
N2586 TNF-a 100
ng/mL
 1
b-NGF
 358.0 33
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
b-NGF
 229.0 40
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 265.0 35
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 320.0 50
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 389.0 61