Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PI103 0.1
uM
 3
IL18
 43.0 83
0
IL18
 12.5 80
RA2159 TNF-a 100
ng/mL
 3
IL18
 139.0 65
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
IL18
 86.5 62
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 105.0 97
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 95.0 52
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 86.0 63
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 40.0 68
RA2159 EO1428 1.0
uM
 3
IL18
 18.0 48
N2586 TNF-a 100
ng/mL
 3
IL18
 217.0 71
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
IL18
 206.0 101
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 206.0 84
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 238.0 79
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 75.0 73
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 170.0 74
N2586 EO1428 1.0
uM
 3
IL18
 64.5 88
0
IL18
 10.0 59
RA2159 3
IL18
 20.0 84
RA2159 PD184352 0.1
uM
 3
IL18
 19.0 59
RA2159 Lestaurtinib 0.3
uM
 3
IL18
 22.0 79
RA2159 Ruxolitinib 0.3
uM
 3
IL18
 19.0 55
RA2159 Tofacitinib 0.3
uM
 3
IL18
 16.0 69
RA2159 IKK16 2.0
uM
 3
IL18
 16.0 54
RA2159 3
IL18
 19.0 76
N2586 3
IL18
 70.0 55