Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL18
 14.0 95
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL18
 20.0 72
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL18
 16.0 63
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IL18
 17.0 54
RA2159 Sigma A6730 3.0
uM
 3
IL18
 20.0 94
N2586 IL-6 100
ug/mL
 3
IL18
 75.0 68
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL18
 56.0 83
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL18
 41.0 62
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL18
 60.0 69
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL18
 41.0 78
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IL18
 37.0 72
N2586 Sigma A6730 3.0
uM
 3
IL18
 46.5 74
RA2159 IL-1 alpha 100
ng/mL
 3
IL18
 45.5 84
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 54.0 75
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 58.0 100
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 60.0 65
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 48.0 87
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 24.0 79
RA2159 PI103 0.1
uM
 3
IL18
 18.0 82
N2586 IL-1 alpha 100
ng/mL
 3
IL18
 168.0 74
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 266.0 76
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 226.5 86
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 252.0 73
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 57.0 70
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 79.0 89