Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | b-NGF | 239.0 | 47 | |
| N2586 | EO1428 | 1.0 | uM | 1 | b-NGF | 88.0 | 61 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 155.0 | 57 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 140.0 | 93 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 103.0 | 60 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 150.0 | 55 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 110.5 | 62 | |
| RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 54.0 | 61 | |
| RA2159 | PI103 | 0.1 | uM | 1 | b-NGF | 49.0 | 48 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 292.0 | 50 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 302.0 | 53 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 308.0 | 57 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 279.0 | 59 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 271.0 | 71 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | b-NGF | 125.0 | 38 | |
| N2586 | PI103 | 0.1 | uM | 1 | b-NGF | 76.0 | 54 | ||||
| RA2159 | IL-6 | 100 | ug/mL | 1 | b-NGF | 45.0 | 71 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 1 | b-NGF | 39.0 | 66 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | b-NGF | 37.5 | 46 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | b-NGF | 45.0 | 68 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 1 | b-NGF | 43.0 | 63 | |
| RA2159 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 1 | b-NGF | 39.0 | 69 | |
| RA2159 | Sigma A6730 | 3.0 | uM | 1 | b-NGF | 55.5 | 74 | ||||
| N2586 | IL-6 | 100 | ug/mL | 1 | b-NGF | 98.0 | 61 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 1 | b-NGF | 107.5 | 48 |