Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 2
TNFb
 61.0 34
N2586 PD184352 0.1
uM
 2
TNFb
 54.0 52
RA2159 IL-1 alpha 100
ng/mL
 2
TNFb
 77.0 64
RA2159 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 74.0 51
RA2159 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 62.0 61
RA2159 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 88.0 59
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 64.0 62
RA2159 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 66.0 60
RA2159 Lestaurtinib 0.3
uM
 2
TNFb
 39.0 68
N2586 IL-1 alpha 100
ng/mL
 2
TNFb
 81.0 64
N2586 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 77.0 57
N2586 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 59.0 62
N2586 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 64.5 42
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 70.0 45
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 53.5 52
N2586 Lestaurtinib 0.3
uM
 2
TNFb
 51.0 63
RA2159 IL-6 100
ug/mL
 2
TNFb
 103.0 50
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
TNFb
 37.0 59
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
TNFb
 86.0 66
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
TNFb
 51.0 50
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
TNFb
 44.5 46
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
TNFb
 58.0 47
RA2159 Ruxolitinib 0.3
uM
 2
TNFb
 56.5 60
N2586 IL-6 100
ug/mL
 2
TNFb
 49.0 49
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
TNFb
 69.0 63