Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
b-NGF
 69.0 56
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
b-NGF
 48.0 58
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
b-NGF
 52.0 64
N2586 Sigma A6730 3.0
uM
 3
b-NGF
 66.0 55
RA2159 IL-1 alpha 100
ng/mL
 3
b-NGF
 75.0 68
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 83.5 58
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 80.0 77
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 109.0 75
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 109.5 48
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 34.5 60
RA2159 PI103 0.1
uM
 3
b-NGF
 33.0 43
N2586 IL-1 alpha 100
ng/mL
 3
b-NGF
 237.0 66
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 293.5 40
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 255.5 54
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 315.0 64
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 61.0 63
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 100.5 60
N2586 PI103 0.1
uM
 3
b-NGF
 50.0 65
0
b-NGF
 7.0 56
RA2159 TNF-a 100
ng/mL
 3
b-NGF
 191.0 55
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
b-NGF
 127.0 53
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
b-NGF
 107.0 80
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
b-NGF
 120.0 39
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
b-NGF
 106.0 74
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
b-NGF
 58.0 60