Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
LIF
 69.0 55
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
LIF
 66.0 59
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
LIF
 75.0 47
RA2159 Sigma A6730 3.0
uM
 3
LIF
 98.0 68
N2586 IL-6 100
ug/mL
 3
LIF
 214.0 64
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
LIF
 117.0 59
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
LIF
 100.0 67
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
LIF
 115.0 51
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
LIF
 88.5 62
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
LIF
 105.0 73
N2586 Sigma A6730 3.0
uM
 3
LIF
 132.0 63
RA2159 IL-1 alpha 100
ng/mL
 3
LIF
 281.5 70
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 170.5 44
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 184.0 62
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 310.0 67
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 274.0 55
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 137.5 62
RA2159 PI103 0.1
uM
 3
LIF
 76.5 52
N2586 IL-1 alpha 100
ng/mL
 3
LIF
 571.5 72
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 440.5 62
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 506.5 66
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 651.5 48
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 198.0 43
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 314.5 74
N2586 PI103 0.1
uM
 3
LIF
 95.0 59