Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 EO1428 1.0
uM
IL-6 100
ug/mL
2
LIF
71.5 50
RA2159 PI103 0.1
uM
IL-6 100
ug/mL
2
LIF
160.5 68
RA2159 Sigma A6730 3.0
uM
IL-6 100
ug/mL
2
LIF
99.0 49
RA2159 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
2
LIF
82.0 59
RA2159 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
2
LIF
115.0 49
RA2159 Ruxolitinib 0.3
uM
2
LIF
96.0 63
N2586 IL-6 100
ug/mL
2
LIF
127.0 67
N2586 EO1428 1.0
uM
IL-6 100
ug/mL
2
LIF
155.0 42
N2586 PI103 0.1
uM
IL-6 100
ug/mL
2
LIF
141.0 55
N2586 Sigma A6730 3.0
uM
IL-6 100
ug/mL
2
LIF
144.0 61
N2586 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
2
LIF
102.0 65
N2586 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
2
LIF
98.0 44
N2586 Ruxolitinib 0.3
uM
2
LIF
135.0 51
RA2159 IL-17A 100
ng/mL
2
LIF
96.0 59
RA2159 EO1428 1.0
uM
IL-17A 100
ng/mL
2
LIF
93.0 50
RA2159 PI103 0.1
uM
IL-17A 100
ng/mL
2
LIF
90.5 54
RA2159 Sigma A6730 3.0
uM
IL-17A 100
ng/mL
2
LIF
114.0 64
RA2159 JNK-IN-8 3.0
uM
IL-17A 100
ng/mL
2
LIF
74.0 65
RA2159 JNK-IN-11 0.3
uM
IL-17A 100
ng/mL
2
LIF
86.5 32
RA2159 Tofacitinib 0.3
uM
2
LIF
87.5 34
N2586 IL-17A 100
ng/mL
2
LIF
134.5 42
N2586 EO1428 1.0
uM
IL-17A 100
ng/mL
2
LIF
186.0 79
N2586 PI103 0.1
uM
IL-17A 100
ng/mL
2
LIF
131.0 13
N2586 Sigma A6730 3.0
uM
IL-17A 100
ng/mL
2
LIF
171.0 28
N2586 JNK-IN-8 3.0
uM
IL-17A 100
ng/mL
2
LIF
146.0 41