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Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling
- Dataset (ID:20232)
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Proteins Studied
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Small molecules
Cells
Proteins
10241:Bortezomib
10367:Navitoclax
51102:HeLa ICRP
51103:HeLa ICRP FLIP-L-mCherry
51104:HeLa ICRP FLIP-S-mCherry
51105:HeLa ICRP Bcl-2-mCherry
51106:HeLa ICRP Bcl-XL-mCherry
201284:TNF10
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Cell
Small Molecule
Small Mol Concentration
Small Mol Conc Unit
Protein
Protein Concentration
Protein Conc Unit
Antibody Name
Antibody Concentration
Antibody Conc Unit
2nd Antibody Name
2nd Antibody Concentration
2nd Antibody Conc Unit
Replicate
Mean log10(k) (a.u.)
Mean tau (min)
Surviving Fraction
Classification Accuracy (theta_T)
Classification Accuracy (fate boundary)
HeLa ICRP Bcl-XL-mCherry
TNF10
25.0
ng/ml
1
-5.09
259.4385
0.914
0.41711
0.39572
HeLa ICRP Bcl-XL-mCherry
TNF10
25.0
ng/ml
2
-5.41
255.1832
0.916
0.65445
0.56021
HeLa ICRP Bcl-XL-mCherry
TNF10
250.0
ng/ml
1
-4.02
64.6000
0.740
0.34000
0.24000
HeLa ICRP Bcl-XL-mCherry
TNF10
250.0
ng/ml
2
-4.19
81.1458
0.917
0.25000
0.08333
HeLa ICRP Bcl-XL-mCherry
TNF10
250.0
ng/ml
3
-4.18
49.8951
0.014
0.90909
0.88112
HeLa ICRP Bcl-XL-mCherry
TNF10
250.0
ng/ml
4
-4.05
77.8723
0.936
0.12766
0.10638
HeLa ICRP Bcl-XL-mCherry
TNF10
250.0
ng/ml
5
-4.01
69.8361
0.836
0.18033
0.13115
HeLa ICRP Bcl-XL-mCherry
TNF10
500.0
ng/ml
1
-4.04
70.9259
0.864
0.20988
0.13580
HeLa ICRP Bcl-XL-mCherry
TNF10
500.0
ng/ml
2
-4.09
66.3725
0.706
0.37255
0.25490
HeLa ICRP Bcl-XL-mCherry
TNF10
500.0
ng/ml
3
-4.18
46.9408
0.007
0.93421
0.83553
HeLa ICRP Bcl-2-mCherry
Navitoclax
10
uM
TNF10
250.0
ng/ml
1
-4.09
48.5371
0.114
0.85590
0.76419
HeLa ICRP Bcl-2-mCherry
Navitoclax
10
uM
TNF10
250.0
ng/ml
2
-4.04
46.3426
0.231
0.80556
0.63889
HeLa ICRP Bcl-XL-mCherry
Navitoclax
10
uM
TNF10
250.0
ng/ml
1
-4.11
52.2500
0.239
0.76111
0.66111
HeLa ICRP Bcl-XL-mCherry
Navitoclax
10
uM
TNF10
250.0
ng/ml
2
-4.03
54.5000
0.400
0.60000
0.50000
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