PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
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| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| MMAC-SF | avg(48,72) | hr | Viability | 4.86730 | 1.46900 |
| LOXIMVI | avg(48,72) | hr | Viability | 3.67010 | 2.61730 |
| RVH-421 | avg(48,72) | hr | Viability | 5.02620 | 0.64800 |
| SKMEL28 | avg(48,72) | hr | Viability | 4.65850 | 1.61170 |
| C32 | avg(48,72) | hr | Viability | 4.99890 | 1.60990 |
| COLO 858 | avg(48,72) | hr | Viability | 5.02770 | 1.02100 |
| K2 | 48 | hr | Viability | 4.12180 | 1.84870 |
| MZ7-mel | avg(48,72) | hr | Viability | 4.85140 | 1.28740 |
| WM1552C | avg(48,72) | hr | Viability | 4.53630 | 2.24070 |
| WM-115 | avg(48,72) | hr | Viability | 4.46100 | 1.73090 |
| MMAC-SF | 5 | hr | Total c-Jun | 1.39460 | 0.87369 |
| COLO 858 | 5 | hr | Total c-Jun | -0.23499 | -0.70922 |
| K2 | 1 | hr | Total c-Jun | 1.55650 | 0.49971 |
| MMAC-SF | 1 | hr | Total c-Jun | 4.07580 | -0.37925 |
| LOXIMVI | 24 | hr | Total c-Jun | 1.82100 | -0.07087 |
| LOXIMVI | 48 | hr | Total c-Jun | 0.87113 | -0.68673 |
| MMAC-SF | 10 | hr | Total c-Jun | 6.82020 | 0.58623 |
| C32 | 10 | hr | Total c-Jun | 6.72650 | -0.50940 |
| COLO 858 | 1 | hr | Total c-Jun | 4.04310 | -0.69013 |
| K2 | 48 | hr | Total c-Jun | -6.49180 | 0.01079 |
| C32 | 1 | hr | Total c-Jun | 1.22180 | 0.50708 |
| C32 | 5 | hr | Total c-Jun | 4.28680 | -0.87148 |
| COLO 858 | 48 | hr | Total c-Jun | -2.62820 | -1.60880 |
| LOXIMVI | 1 | hr | Total c-Jun | 1.62440 | -0.88426 |
| LOXIMVI | 5 | hr | Total c-Jun | 1.35000 | 0.37604 |