Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| JNK-IN-8 | COLO 858 | 0.0033 | uM | 24 | hr | | Ki-67 | 2318.80 | p-Rb(S807/S811) | 153.43 | p-cJun(S73) | 29.19 | 2 | Colo858-signal3 | E10 | |
| JNK-IN-8 | COLO 858 | 0.0000 | uM | 24 | hr | | Ki-67 | 2266.10 | p-Rb(S807/S811) | 152.55 | p-cJun(S73) | 28.74 | 2 | Colo858-signal3 | E11 | |
| JNK-IN-8 | COLO 858 | 5.0000 | uM | 24 | hr | | Ki-67 | 2634.30 | p-Rb(S807/S811) | 252.91 | p-cJun(S73) | 39.50 | 2 | Colo858-signal3 | E2 | |
| JNK-IN-8 | COLO 858 | 2.0000 | uM | 24 | hr | | Ki-67 | 2641.30 | p-Rb(S807/S811) | 226.22 | p-cJun(S73) | 34.79 | 2 | Colo858-signal3 | E3 | |
| JNK-IN-8 | COLO 858 | 0.8000 | uM | 24 | hr | | Ki-67 | 2394.30 | p-Rb(S807/S811) | 184.89 | p-cJun(S73) | 30.67 | 2 | Colo858-signal3 | E4 | |
| JNK-IN-8 | COLO 858 | 0.3200 | uM | 24 | hr | | Ki-67 | 2300.70 | p-Rb(S807/S811) | 172.32 | p-cJun(S73) | 30.64 | 2 | Colo858-signal3 | E5 | |
| JNK-IN-8 | COLO 858 | 0.1280 | uM | 24 | hr | | Ki-67 | 2233.20 | p-Rb(S807/S811) | 162.30 | p-cJun(S73) | 29.52 | 2 | Colo858-signal3 | E6 | |
| JNK-IN-8 | COLO 858 | 0.0512 | uM | 24 | hr | | Ki-67 | 2172.00 | p-Rb(S807/S811) | 160.38 | p-cJun(S73) | 29.06 | 2 | Colo858-signal3 | E7 | |
| JNK-IN-8 | COLO 858 | 0.0205 | uM | 24 | hr | | Ki-67 | 2269.90 | p-Rb(S807/S811) | 156.97 | p-cJun(S73) | 29.44 | 2 | Colo858-signal3 | E8 | |
| JNK-IN-8 | COLO 858 | 0.0082 | uM | 24 | hr | | Ki-67 | 2294.40 | p-Rb(S807/S811) | 151.40 | p-cJun(S73) | 29.18 | 2 | Colo858-signal3 | E9 | |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2257.40 | p-Rb(S807/S811) | 152.83 | p-cJun(S73) | 28.15 | 1 | Colo858-signal3 | F10 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 2257.00 | p-Rb(S807/S811) | 151.09 | p-cJun(S73) | 29.94 | 1 | Colo858-signal3 | F11 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 1967.00 | p-Rb(S807/S811) | 99.41 | p-cJun(S73) | 22.51 | 1 | Colo858-signal3 | F2 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 2.0000 | uM | 24 | hr | | Ki-67 | 1130.80 | p-Rb(S807/S811) | 51.60 | p-cJun(S73) | 14.98 | 1 | Colo858-signal3 | F3 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.8000 | uM | 24 | hr | | Ki-67 | 807.26 | p-Rb(S807/S811) | 48.49 | p-cJun(S73) | 14.54 | 1 | Colo858-signal3 | F4 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.3200 | uM | 24 | hr | | Ki-67 | 797.23 | p-Rb(S807/S811) | 51.78 | p-cJun(S73) | 20.45 | 1 | Colo858-signal3 | F5 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.1280 | uM | 24 | hr | | Ki-67 | 1090.60 | p-Rb(S807/S811) | 84.26 | p-cJun(S73) | 33.13 | 1 | Colo858-signal3 | F6 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.0512 | uM | 24 | hr | | Ki-67 | 1684.50 | p-Rb(S807/S811) | 129.01 | p-cJun(S73) | 29.91 | 1 | Colo858-signal3 | F7 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.0205 | uM | 24 | hr | | Ki-67 | 2146.20 | p-Rb(S807/S811) | 150.60 | p-cJun(S73) | 28.79 | 1 | Colo858-signal3 | F8 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.0082 | uM | 24 | hr | | Ki-67 | 2177.30 | p-Rb(S807/S811) | 151.57 | p-cJun(S73) | 28.39 | 1 | Colo858-signal3 | F9 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2368.00 | p-Rb(S807/S811) | 158.88 | p-cJun(S73) | 29.06 | 2 | Colo858-signal3 | G10 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 2392.50 | p-Rb(S807/S811) | 158.97 | p-cJun(S73) | 29.83 | 2 | Colo858-signal3 | G11 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 2211.10 | p-Rb(S807/S811) | 96.70 | p-cJun(S73) | 24.08 | 2 | Colo858-signal3 | G2 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 2.0000 | uM | 24 | hr | | Ki-67 | 1116.10 | p-Rb(S807/S811) | 51.88 | p-cJun(S73) | 15.04 | 2 | Colo858-signal3 | G3 |
| Vemurafenib | COLO 858 | JNK-IN-8 | 0.8000 | uM | 24 | hr | | Ki-67 | 747.98 | p-Rb(S807/S811) | 47.12 | p-cJun(S73) | 13.64 | 2 | Colo858-signal3 | G4 |