Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by Reverse Phase Protein Arrays (RPPA) - Dataset - HMS LINCS Database

Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by Reverse Phase Protein Arrays (RPPA) - Dataset (ID:20218)

August 25, 2015: The data file for this dataset was updated to include additional DMSO control data that were inadvertently omitted from the original version. The Assay Protocol description of how experimental data were normalized to DMSO control data also was clarified (point 9).

Full screen view

Download: Excel (XLSX), Comma-separated (CSV)

Filter results: >>>>

|<
<<
Previous
Page 116 of 1308
Next
>>
>
2876 to 2900 of 32680 records
per page:

Small Molecule	Cell Line	Drug Concentration	Conc Unit	Time Point	Time Point Unit	Replicate	Scanner/Software	pMEK(S217/221)	Normalized Median pMEK(S217/221)	pERK(T202/Y204)	Normalized Median pERK(T202/Y204)	p-p90RSK(S380)	Normalized Median p-p90RSK(S380)	p-p90RSK(T573)	Normalized Median p-p90RSK(T573)	p-AKT(T308)	Normalized Median p-AKT(T308)	p-AKT(S473)	Normalized Median p-AKT(S473)	p-mTOR(S2448)	Normalized Median p-mTOR(S2448)	p-p70S6K(T421/S424)	Normalized Median p-p70S6K(T421/S424)	p-p70S6K(T389)	Normalized Median p-p70S6K(T389)	p-S6(S235/236)	Normalized Median p-S6(S235/236)	p-AMPK(T172)	Normalized Median p-AMPK(T172)	p-JNK(T183/Y185)	Normalized Median p-JNK(T183/Y185)	Total c-Jun	Normalized Median Total c-Jun	p-cJun(S63)	Normalized Median p-cJun(S63)	p-P38(T180/Y182)	Normalized Median p-P38(T180/Y182)	p-HSP27(S82)	Normalized Median p-HSP27(S82)	p-NFKB(S536)	Normalized Median p-NFKB(S536)	Bim	Normalized Median Bim	cPARP	Normalized Median cPARP	p-Histone H3(S10)	Normalized Median p-Histone H3(S10)	p27 Kip1	Normalized Median p27 Kip1
AZ-628	COLO 858	0.0032	uM	48	hr	4	InnoScan/Mapix	0.0529	0.1606	1.0989	1.0843	0.0041	0.0510	0.0035	0.1058	0.0220	0.7777	0.0226	0.6653	0.0108	0.3934	0.0167	0.2949	0.0618	-0.3321	0.4695	0.2679	0.0412	-0.6026	0.0031	0.1788	0.0246	0.4066	0.0126	0.5507	0.0544	0.9575	0.0056	-0.1352	0.1473	0.8766	0.0300	0.9522	0.0121	0.8378	0.2584	1.1408	0.0201	0.3172
AZ-628	COLO 858	0.0032	uM	48	hr	5	InnoScan/Mapix	0.0640	0.1606	0.7299	1.0843	0.0048	0.0510	0.0044	0.1058	0.0093	0.7777	0.0096	0.6653	0.0119	0.3934	0.0233	0.2949	0.0467	-0.3321	0.4386	0.2679	0.0404	-0.6026	0.0040	0.1788	0.0205	0.4066	0.0117	0.5507	0.0327	0.9575	0.0040	-0.1352	0.0980	0.8766	0.0159	0.9522	0.0116	0.8378	0.1605	1.1408	0.0186	0.3172
AZ-628	COLO 858	0.0032	uM	48	hr	6	InnoScan/Mapix	0.0573	0.1606	1.3699	1.0843	0.0042	0.0510	0.0035	0.1058	0.0107	0.7777	0.0114	0.6653	0.0129	0.3934	0.0207	0.2949	0.0509	-0.3321	0.4464	0.2679	0.0444	-0.6026	0.0038	0.1788	0.0232	0.4066	0.0120	0.5507	0.0460	0.9575	0.0050	-0.1352	0.1065	0.8766	0.0184	0.9522	0.0136	0.8378	0.2257	1.1408	0.0217	0.3172
AZ-628	COLO 858	0.0032	uM	48	hr	7	InnoScan/Mapix	0.0497	0.1606	0.8929	1.0843	0.0043	0.0510	0.0037	0.1058	0.0137	0.7777	0.0125	0.6653	0.0116	0.3934	0.0184	0.2949	0.0478	-0.3321	0.5155	0.2679	0.0382	-0.6026	0.0035	0.1788	0.0227	0.4066	0.0109	0.5507	0.0329	0.9575	0.0072	-0.1352	0.1075	0.8766	0.0192	0.9522	0.0120	0.8378	0.1942	1.1408	0.0194	0.3172
AZ-628	COLO 858	0.0032	uM	48	hr	8	InnoScan/Mapix	0.0534	0.1606	1.0309	1.0843	0.0044	0.0510	0.0041	0.1058	0.0145	0.7777	0.0155	0.6653	0.0123	0.3934	0.0187	0.2949	0.0466	-0.3321	0.4717	0.2679	0.0451	-0.6026	0.0036	0.1788	0.0255	0.4066	0.0130	0.5507	0.0490	0.9575	0.0056	-0.1352	0.1182	0.8766	0.0251	0.9522	0.0134	0.8378	0.2283	1.1408	0.0229	0.3172
AZ-628	COLO 858	0.0100	uM	1	hr	1	InnoScan/Mapix	0.0224	-1.0209	0.3831	-0.0637	0.0037	-0.1404	0.0037	0.2326	0.0132	1.3790	0.0121	1.4031	0.0086	0.3879	0.0151	0.1954	0.0408	-0.2888	0.5076	0.5714	0.0511	-0.0242	0.0034	0.5681	0.0240	0.5969		0.4122	0.0199	-0.0718	0.0077	0.1656	0.0629	0.3830	0.0226	1.5607	0.0140	1.0417	0.1242	0.9349	0.0183	0.3319
AZ-628	COLO 858	0.0100	uM	1	hr	2	InnoScan/Mapix	0.0233	-1.0209	0.4049	-0.0637	0.0035	-0.1404	0.0036	0.2326	0.0139	1.3790	0.0155	1.4031	0.0089	0.3879	0.0152	0.1954	0.0563	-0.2888	0.4608	0.5714	0.0559	-0.0242	0.0037	0.5681	0.0249	0.5969	0.0092	0.4122	0.0216	-0.0718	0.0043	0.1656	0.0663	0.3830	0.0226	1.5607	0.0140	1.0417	0.1468	0.9349	0.0168	0.3319
AZ-628	COLO 858	0.0100	uM	1	hr	3	InnoScan/Mapix	0.0274	-1.0209	0.3759	-0.0637	0.0038	-0.1404	0.0046	0.2326	0.0179	1.3790	0.0181	1.4031	0.0114	0.3879	0.0200	0.1954	0.0625	-0.2888	0.5236	0.5714	0.0641	-0.0242	0.0044	0.5681	0.0249	0.5969	0.0114	0.4122	0.0193	-0.0718	0.0104	0.1656	0.0761	0.3830	0.0264	1.5607	0.0158	1.0417	0.1776	0.9349	0.0205	0.3319
AZ-628	COLO 858	0.0100	uM	1	hr	4	InnoScan/Mapix	0.0290	-1.0209	0.3937	-0.0637	0.0043	-0.1404	0.0057	0.2326	0.0189	1.3790	0.0219	1.4031	0.0148	0.3879	0.0240	0.1954	0.0549	-0.2888	0.4951	0.5714	0.0670	-0.0242	0.0057	0.5681	0.0277	0.5969	0.0104	0.4122	0.0250	-0.0718	0.0046	0.1656	0.0745	0.3830	0.0322	1.5607	0.0113	1.0417	0.1859	0.9349	0.0239	0.3319
AZ-628	COLO 858	0.0100	uM	1	hr	5	InnoScan/Mapix	0.0224	-1.0209	0.4630	-0.0637	0.0037	-0.1404	0.0039	0.2326	0.0162	1.3790	0.0195	1.4031	0.0108	0.3879	0.0165	0.1954	0.0415	-0.2888	0.7299	0.5714	0.0578	-0.0242	0.0049	0.5681	0.0261	0.5969	0.0099	0.4122	0.0212	-0.0718	0.0068	0.1656	0.0849	0.3830	0.0319	1.5607	0.0158	1.0417	0.1468	0.9349	0.0230	0.3319
AZ-628	COLO 858	0.0100	uM	1	hr	6	InnoScan/Mapix	0.0232	-1.0209	0.4951	-0.0637	0.0038	-0.1404	0.0041	0.2326	0.0198	1.3790	0.0238	1.4031	0.0121	0.3879	0.0187	0.1954	0.0440	-0.2888	0.6944	0.5714	0.0575	-0.0242	0.0052	0.5681	0.0283	0.5969	0.0104	0.4122	0.0208	-0.0718	0.0048	0.1656	0.0902	0.3830		1.5607	0.0106	1.0417	0.1761	0.9349	0.0222	0.3319
AZ-628	COLO 858	0.0100	uM	1	hr	7	InnoScan/Mapix	0.0254	-1.0209	0.4651	-0.0637	0.0038	-0.1404	0.0035	0.2326	0.0214	1.3790	0.0251	1.4031	0.0122	0.3879	0.0157	0.1954	0.0529	-0.2888	0.6098	0.5714	0.0737	-0.0242	0.0041	0.5681	0.0251	0.5969	0.0091	0.4122	0.0187	-0.0718	0.0152	0.1656	0.0796	0.3830	0.0300	1.5607	0.0138	1.0417	0.1709	0.9349	0.0202	0.3319
AZ-628	COLO 858	0.0100	uM	1	hr	8	InnoScan/Mapix	0.0285	-1.0209	0.4808	-0.0637		-0.1404	0.0065	0.2326	0.0246	1.3790	0.0308	1.4031	0.0164	0.3879	0.0236	0.1954	0.0519	-0.2888	0.6098	0.5714	0.0760	-0.0242	0.0065	0.5681	0.0302	0.5969	0.0103	0.4122		-0.0718	0.0070	0.1656	0.0828	0.3830	0.0355	1.5607	0.0125	1.0417	0.1786	0.9349	0.0255	0.3319
AZ-628	COLO 858	0.0100	uM	5	hr	1	InnoScan/Mapix	0.0228	-1.1134	0.6250	0.3345	0.0037	-0.1542	0.0038	0.1596	0.0122	0.7810	0.0134	1.0833	0.0080	-0.1423	0.0159	0.0571	0.0439	-0.4536	0.7353	0.7769	0.0337	-0.8615	0.0033	0.0868	0.0206	0.2097	0.0094	0.1218	0.0308	0.3603	0.0073	-0.4184	0.0838	0.4996	0.0213	0.9372	0.0116	0.6214	0.1100	0.5452	0.0168	-0.0251
AZ-628	COLO 858	0.0100	uM	5	hr	2	InnoScan/Mapix	0.0228	-1.1134	0.6623	0.3345	0.0035	-0.1542	0.0039	0.1596	0.0122	0.7810	0.0165	1.0833	0.0082	-0.1423	0.0161	0.0571	0.0497	-0.4536	0.6579	0.7769	0.0371	-0.8615	0.0035	0.0868	0.0211	0.2097	0.0090	0.1218	0.0399	0.3603	0.0040	-0.4184	0.0872	0.4996	0.0187	0.9372	0.0130	0.6214	0.1362	0.5452	0.0178	-0.0251
AZ-628	COLO 858	0.0100	uM	5	hr	3	InnoScan/Mapix	0.0228	-1.1134	0.6369	0.3345	0.0039	-0.1542	0.0039	0.1596	0.0144	0.7810	0.0166	1.0833	0.0080	-0.1423	0.0160	0.0571	0.0534	-0.4536	0.6993	0.7769	0.0334	-0.8615	0.0032	0.0868	0.0202	0.2097	0.0090	0.1218	0.0283	0.3603	0.0084	-0.4184	0.0992	0.4996	0.0186	0.9372	0.0111	0.6214	0.1499	0.5452	0.0165	-0.0251
AZ-628	COLO 858	0.0100	uM	5	hr	4	InnoScan/Mapix	0.0241	-1.1134	0.6250	0.3345	0.0039	-0.1542	0.0044	0.1596	0.0113	0.7810	0.0197	1.0833	0.0102	-0.1423	0.0184	0.0571	0.0485	-0.4536	0.6849	0.7769	0.0353	-0.8615	0.0041	0.0868	0.0215	0.2097	0.0086	0.1218	0.0372	0.3603	0.0030	-0.4184	0.0989	0.4996	0.0215	0.9372	0.0086	0.6214	0.1698	0.5452	0.0215	-0.0251
AZ-628	COLO 858	0.0100	uM	5	hr	5	InnoScan/Mapix	0.0218	-1.1134	0.4464	0.3345		-0.1542	0.0033	0.1596	0.0096	0.7810	0.0118	1.0833	0.0074	-0.1423	0.0136	0.0571	0.0481	-0.4536	0.6452	0.7769	0.0367	-0.8615	0.0028	0.0868	0.0166	0.2097	0.0083	0.1218	0.0185	0.3603	0.0044	-0.4184	0.0816	0.4996	0.0161	0.9372	0.0114	0.6214	0.1217	0.5452	0.0147	-0.0251
AZ-628	COLO 858	0.0100	uM	5	hr	6	InnoScan/Mapix	0.0219	-1.1134	0.4785	0.3345	0.0034	-0.1542	0.0035	0.1596	0.0099	0.7810	0.0137	1.0833	0.0075	-0.1423	0.0142	0.0571	0.0455	-0.4536	0.6135	0.7769	0.0345	-0.8615	0.0034	0.0868	0.0176	0.2097	0.0083	0.1218	0.0201	0.3603	0.0048	-0.4184	0.0850	0.4996		0.9372	0.0068	0.6214	0.1416	0.5452	0.0163	-0.0251
AZ-628	COLO 858	0.0100	uM	5	hr	7	InnoScan/Mapix	0.0241	-1.1134	0.5208	0.3345	0.0033	-0.1542	0.0034	0.1596	0.0136	0.7810	0.0168	1.0833	0.0087	-0.1423	0.0141	0.0571	0.0405	-0.4536	0.6211	0.7769	0.0333	-0.8615	0.0032	0.0868	0.0180	0.2097	0.0076	0.1218	0.0183	0.3603	0.0040	-0.4184	0.0754	0.4996	0.0195	0.9372	0.0097	0.6214	0.1226	0.5452	0.0159	-0.0251
AZ-628	COLO 858	0.0100	uM	5	hr	8	InnoScan/Mapix	0.0249	-1.1134	0.4785	0.3345	0.0043	-0.1542	0.0051	0.1596	0.0124	0.7810	0.0202	1.0833	0.0110	-0.1423	0.0198	0.0571	0.0425	-0.4536	0.6329	0.7769	0.0326	-0.8615	0.0046	0.0868	0.0190	0.2097	0.0079	0.1218	0.0278	0.3603	0.0057	-0.4184	0.0754	0.4996	0.0219	0.9372	0.0095	0.6214	0.1287	0.5452	0.0192	-0.0251
AZ-628	COLO 858	0.0100	uM	10	hr	1	InnoScan/Mapix	0.0337	-0.2726	0.3876	0.4526	0.0039	0.1672	0.0044	0.6827	0.0141	1.0855	0.0122	1.0487	0.0085	0.6117	0.0191	0.8337		-0.1239	0.3086	-0.0663	0.0984	0.9175	0.0034	0.5936	0.0192	0.5787	0.0088	0.1943	0.0155	-0.1404	0.0050	-0.3468	0.0939	1.0770	0.0238	1.5507	0.0087	0.6008	0.0815	0.4027	0.0217	0.5919
AZ-628	COLO 858	0.0100	uM	10	hr	2	InnoScan/Mapix	0.0327	-0.2726	0.4405	0.4526	0.0037	0.1672	0.0041	0.6827	0.0141	1.0855	0.0117	1.0487	0.0091	0.6117	0.0174	0.8337	0.0563	-0.1239	0.2890	-0.0663	0.1032	0.9175	0.0038	0.5936	0.0203	0.5787	0.0082	0.1943	0.0198	-0.1404	0.0045	-0.3468	0.1038	1.0770	0.0208	1.5507	0.0088	0.6008	0.0971	0.4027	0.0202	0.5919
AZ-628	COLO 858	0.0100	uM	10	hr	3	InnoScan/Mapix	0.0428	-0.2726	0.4367	0.4526	0.0046	0.1672	0.0058	0.6827	0.0178	1.0855	0.0155	1.0487	0.0134	0.6117	0.0271	0.8337	0.0588	-0.1239	0.3745	-0.0663	0.1486	0.9175	0.0045	0.5936	0.0214	0.5787	0.0083	0.1943	0.0151	-0.1404	0.0028	-0.3468	0.1221	1.0770	0.0297	1.5507	0.0105	0.6008	0.1066	0.4027	0.0273	0.5919
AZ-628	COLO 858	0.0100	uM	10	hr	4	InnoScan/Mapix	0.0456	-0.2726	0.4525	0.4526	0.0052	0.1672	0.0064	0.6827	0.0144	1.0855	0.0201	1.0487	0.0174	0.6117	0.0319	0.8337	0.0609	-0.1239	0.3521	-0.0663	0.1332	0.9175	0.0059	0.5936	0.0233	0.5787	0.0082	0.1943	0.0209	-0.1404	0.0044	-0.3468	0.1272	1.0770	0.0340	1.5507	0.0084	0.6008	0.1112	0.4027	0.0307	0.5919

|<
<<
Previous
Page 116 of 1308
Next
>>
>
2876 to 2900 of 32680 records
per page:

HMS LINCS Project

Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by Reverse Phase Protein Arrays (RPPA) - Dataset (ID:20218)