Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | RVH-421 | 0.1000 | uM | 48 | hr | 1453 | 112 | 0.7007 | 0.7209 | 0.0771 | 0.0642 | 1 |
| Selumetinib | RVH-421 | 0.1000 | uM | 48 | hr | 1356 | 92 | 0.6604 | 0.7209 | 0.0678 | 0.0642 | 2 |
| Selumetinib | RVH-421 | 0.1000 | uM | 48 | hr | 1521 | 71 | 0.7576 | 0.7209 | 0.0467 | 0.0642 | 3 |
| Selumetinib | RVH-421 | 0.1000 | uM | 48 | hr | 1566 | 102 | 0.7649 | 0.7209 | 0.0651 | 0.0642 | 4 |
| Selumetinib | RVH-421 | 0.1000 | uM | 72 | hr | 6016 | 311 | 0.6537 | 0.6575 | 0.0517 | 0.0418 | 1 |
| Selumetinib | RVH-421 | 0.1000 | uM | 72 | hr | 6854 | 239 | 0.7580 | 0.6575 | 0.0349 | 0.0418 | 2 |
| Selumetinib | RVH-421 | 0.1000 | uM | 72 | hr | 5644 | 200 | 0.6238 | 0.6575 | 0.0354 | 0.0418 | 3 |
| Selumetinib | RVH-421 | 0.1000 | uM | 72 | hr | 5432 | 245 | 0.5944 | 0.6575 | 0.0451 | 0.0418 | 4 |
| Selumetinib | RVH-421 | 0.3160 | uM | 24 | hr | 1582 | 82 | 1.0851 | 1.0935 | 0.0518 | 0.0515 | 1 |
| Selumetinib | RVH-421 | 0.3160 | uM | 24 | hr | 1605 | 82 | 1.1018 | 1.0935 | 0.0511 | 0.0515 | 2 |
| Selumetinib | RVH-421 | 0.3160 | uM | 24 | hr | 3 | ||||||
| Selumetinib | RVH-421 | 0.3160 | uM | 24 | hr | 4 | ||||||
| Selumetinib | RVH-421 | 0.3160 | uM | 48 | hr | 1477 | 105 | 0.7169 | 0.6591 | 0.0711 | 0.0635 | 1 |
| Selumetinib | RVH-421 | 0.3160 | uM | 48 | hr | 1226 | 82 | 0.5977 | 0.6591 | 0.0669 | 0.0635 | 2 |
| Selumetinib | RVH-421 | 0.3160 | uM | 48 | hr | 1320 | 69 | 0.6537 | 0.6591 | 0.0523 | 0.0635 | 3 |
| Selumetinib | RVH-421 | 0.3160 | uM | 48 | hr | 1366 | 87 | 0.6683 | 0.6591 | 0.0637 | 0.0635 | 4 |
| Selumetinib | RVH-421 | 0.3160 | uM | 72 | hr | 4966 | 200 | 0.5461 | 0.5657 | 0.0403 | 0.0438 | 1 |
| Selumetinib | RVH-421 | 0.3160 | uM | 72 | hr | 6040 | 262 | 0.6621 | 0.5657 | 0.0434 | 0.0438 | 2 |
| Selumetinib | RVH-421 | 0.3160 | uM | 72 | hr | 4671 | 239 | 0.5079 | 0.5657 | 0.0512 | 0.0438 | 3 |
| Selumetinib | RVH-421 | 0.3160 | uM | 72 | hr | 4972 | 201 | 0.5467 | 0.5657 | 0.0404 | 0.0438 | 4 |
| Selumetinib | RVH-421 | 1.0000 | uM | 24 | hr | 1475 | 70 | 1.0164 | 1.0164 | 0.0475 | 0.0523 | 1 |
| Selumetinib | RVH-421 | 1.0000 | uM | 24 | hr | 1490 | 85 | 1.0164 | 1.0164 | 0.0570 | 0.0523 | 2 |
| Selumetinib | RVH-421 | 1.0000 | uM | 24 | hr | 3 | ||||||
| Selumetinib | RVH-421 | 1.0000 | uM | 24 | hr | 4 | ||||||
| Selumetinib | RVH-421 | 1.0000 | uM | 48 | hr | 1306 | 103 | 0.6286 | 0.6582 | 0.0789 | 0.0671 | 1 |