Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | RVH-421 | 0.1000 | uM | 48 | hr | 1486 | 72 | 0.7388 | 0.6891 | 0.0485 | 0.0578 | 3 |
| SB590885 | RVH-421 | 0.1000 | uM | 48 | hr | 1553 | 89 | 0.7649 | 0.6891 | 0.0573 | 0.0578 | 4 |
| SB590885 | RVH-421 | 0.1000 | uM | 72 | hr | 6638 | 294 | 0.7270 | 0.7018 | 0.0443 | 0.0440 | 1 |
| SB590885 | RVH-421 | 0.1000 | uM | 72 | hr | 6470 | 250 | 0.7128 | 0.7018 | 0.0386 | 0.0440 | 2 |
| SB590885 | RVH-421 | 0.1000 | uM | 72 | hr | 6156 | 281 | 0.6732 | 0.7018 | 0.0456 | 0.0440 | 3 |
| SB590885 | RVH-421 | 0.1000 | uM | 72 | hr | 6362 | 302 | 0.6944 | 0.7018 | 0.0475 | 0.0440 | 4 |
| SB590885 | RVH-421 | 0.3160 | uM | 24 | hr | 1447 | 90 | 0.9817 | 1.0121 | 0.0622 | 0.0536 | 1 |
| SB590885 | RVH-421 | 0.3160 | uM | 24 | hr | 1509 | 68 | 1.0425 | 1.0121 | 0.0451 | 0.0536 | 2 |
| SB590885 | RVH-421 | 0.3160 | uM | 24 | hr | 3 | ||||||
| SB590885 | RVH-421 | 0.3160 | uM | 24 | hr | 4 | ||||||
| SB590885 | RVH-421 | 0.3160 | uM | 48 | hr | 1462 | 80 | 0.7221 | 0.6721 | 0.0547 | 0.0567 | 1 |
| SB590885 | RVH-421 | 0.3160 | uM | 48 | hr | 1398 | 92 | 0.6824 | 0.6721 | 0.0658 | 0.0567 | 2 |
| SB590885 | RVH-421 | 0.3160 | uM | 48 | hr | 1249 | 66 | 0.6181 | 0.6721 | 0.0528 | 0.0567 | 3 |
| SB590885 | RVH-421 | 0.3160 | uM | 48 | hr | 1346 | 72 | 0.6657 | 0.6721 | 0.0535 | 0.0567 | 4 |
| SB590885 | RVH-421 | 0.3160 | uM | 72 | hr | 6332 | 273 | 0.6943 | 0.6412 | 0.0431 | 0.0408 | 1 |
| SB590885 | RVH-421 | 0.3160 | uM | 72 | hr | 5850 | 223 | 0.6448 | 0.6412 | 0.0381 | 0.0408 | 2 |
| SB590885 | RVH-421 | 0.3160 | uM | 72 | hr | 5525 | 247 | 0.6048 | 0.6412 | 0.0447 | 0.0408 | 3 |
| SB590885 | RVH-421 | 0.3160 | uM | 72 | hr | 5629 | 209 | 0.6211 | 0.6412 | 0.0371 | 0.0408 | 4 |
| SB590885 | RVH-421 | 1.0000 | uM | 24 | hr | 1470 | 92 | 0.9969 | 1.0244 | 0.0626 | 0.0620 | 1 |
| SB590885 | RVH-421 | 1.0000 | uM | 24 | hr | 1549 | 95 | 1.0519 | 1.0244 | 0.0613 | 0.0620 | 2 |
| SB590885 | RVH-421 | 1.0000 | uM | 24 | hr | 3 | ||||||
| SB590885 | RVH-421 | 1.0000 | uM | 24 | hr | 4 | ||||||
| SB590885 | RVH-421 | 1.0000 | uM | 48 | hr | 1366 | 115 | 0.6537 | 0.6378 | 0.0842 | 0.0708 | 1 |
| SB590885 | RVH-421 | 1.0000 | uM | 48 | hr | 1391 | 112 | 0.6683 | 0.6378 | 0.0805 | 0.0708 | 2 |
| SB590885 | RVH-421 | 1.0000 | uM | 48 | hr | 1232 | 74 | 0.6051 | 0.6378 | 0.0601 | 0.0708 | 3 |