Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | RVH-421 | 0.3160 | uM | 72 | hr | 5506 | 280 | 0.5988 | 0.6782 | 0.0509 | 0.0466 | 3 |
| PLX-4720 | RVH-421 | 0.3160 | uM | 72 | hr | 6188 | 278 | 0.6772 | 0.6782 | 0.0449 | 0.0466 | 4 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 24 | hr | 1456 | 66 | 1.0056 | 0.9813 | 0.0453 | 0.0478 | 1 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 24 | hr | 1393 | 70 | 0.9571 | 0.9813 | 0.0503 | 0.0478 | 2 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | RVH-421 | 1.0000 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | RVH-421 | 1.0000 | uM | 48 | hr | 1418 | 89 | 0.6944 | 0.6734 | 0.0628 | 0.0593 | 1 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 48 | hr | 1282 | 76 | 0.6301 | 0.6734 | 0.0593 | 0.0593 | 2 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 48 | hr | 1382 | 93 | 0.6735 | 0.6734 | 0.0673 | 0.0593 | 3 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 48 | hr | 1398 | 67 | 0.6955 | 0.6734 | 0.0479 | 0.0593 | 4 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 72 | hr | 5433 | 267 | 0.5920 | 0.5689 | 0.0491 | 0.0510 | 1 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 72 | hr | 5484 | 281 | 0.5962 | 0.5689 | 0.0512 | 0.0510 | 2 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 72 | hr | 4550 | 276 | 0.4898 | 0.5689 | 0.0607 | 0.0510 | 3 |
| PLX-4720 | RVH-421 | 1.0000 | uM | 72 | hr | 5448 | 234 | 0.5975 | 0.5689 | 0.0430 | 0.0510 | 4 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 24 | hr | 1307 | 76 | 0.8905 | 0.9086 | 0.0581 | 0.0574 | 1 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 24 | hr | 1358 | 77 | 0.9267 | 0.9086 | 0.0567 | 0.0574 | 2 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | RVH-421 | 3.1600 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | RVH-421 | 3.1600 | uM | 48 | hr | 1261 | 126 | 0.5930 | 0.5407 | 0.0999 | 0.0831 | 1 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 48 | hr | 1066 | 107 | 0.5011 | 0.5407 | 0.1004 | 0.0831 | 2 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 48 | hr | 1133 | 80 | 0.5502 | 0.5407 | 0.0706 | 0.0831 | 3 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 48 | hr | 1057 | 65 | 0.5183 | 0.5407 | 0.0615 | 0.0831 | 4 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 72 | hr | 4430 | 319 | 0.4711 | 0.4833 | 0.0720 | 0.0617 | 1 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 72 | hr | 4385 | 314 | 0.4665 | 0.4833 | 0.0716 | 0.0617 | 2 |
| PLX-4720 | RVH-421 | 3.1600 | uM | 72 | hr | 4540 | 233 | 0.4935 | 0.4833 | 0.0513 | 0.0617 | 3 |