Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 RVH-421 3.1600
uM
 72
hr
 4620 239 0.5020 0.4833 0.0517 0.0617 4
AZ-628 RVH-421 0.0032
uM
 24
hr
 1271 68 0.8703 0.9289 0.0535 0.0557 1
AZ-628 RVH-421 0.0032
uM
 24
hr
 1449 84 0.9875 0.9289 0.0580 0.0557 2
AZ-628 RVH-421 0.0032
uM
 24
hr
 3
AZ-628 RVH-421 0.0032
uM
 24
hr
 4
AZ-628 RVH-421 0.0032
uM
 48
hr
 2390 153 1.1688 1.0628 0.0640 0.0503 1
AZ-628 RVH-421 0.0032
uM
 48
hr
 2176 97 1.0863 1.0628 0.0446 0.0503 2
AZ-628 RVH-421 0.0032
uM
 48
hr
 2026 108 1.0022 1.0628 0.0533 0.0503 3
AZ-628 RVH-421 0.0032
uM
 48
hr
 1980 78 0.9938 1.0628 0.0394 0.0503 4
AZ-628 RVH-421 0.0032
uM
 72
hr
 8309 249 0.9236 0.9565 0.0300 0.0338 1
AZ-628 RVH-421 0.0032
uM
 72
hr
 9263 338 1.0227 0.9565 0.0365 0.0338 2
AZ-628 RVH-421 0.0032
uM
 72
hr
 8488 275 0.9411 0.9565 0.0324 0.0338 3
AZ-628 RVH-421 0.0032
uM
 72
hr
 8498 308 0.9385 0.9565 0.0362 0.0338 4
AZ-628 RVH-421 0.0100
uM
 24
hr
 1395 71 0.9578 0.9636 0.0509 0.0513 1
AZ-628 RVH-421 0.0100
uM
 24
hr
 1413 73 0.9694 0.9636 0.0517 0.0513 2
AZ-628 RVH-421 0.0100
uM
 24
hr
 3
AZ-628 RVH-421 0.0100
uM
 24
hr
 4
AZ-628 RVH-421 0.0100
uM
 48
hr
 2010 128 0.9834 0.9440 0.0637 0.0530 1
AZ-628 RVH-421 0.0100
uM
 48
hr
 1855 86 0.9243 0.9440 0.0464 0.0530 2
AZ-628 RVH-421 0.0100
uM
 48
hr
 1865 97 0.9238 0.9440 0.0520 0.0530 3
AZ-628 RVH-421 0.0100
uM
 48
hr
 1903 95 0.9447 0.9440 0.0499 0.0530 4
AZ-628 RVH-421 0.0100
uM
 72
hr
 8300 287 0.9182 0.9153 0.0346 0.0320 1
AZ-628 RVH-421 0.0100
uM
 72
hr
 8925 283 0.9903 0.9153 0.0317 0.0320 2
AZ-628 RVH-421 0.0100
uM
 72
hr
 7129 193 0.7948 0.9153 0.0271 0.0320 3
AZ-628 RVH-421 0.0100
uM
 72
hr
 8657 299 0.9577 0.9153 0.0345 0.0320 4