Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | C32 | 1.0000 | uM | 48 | hr | 1975 | 754 | 0.5941 | 0.5507 | 0.3818 | 0.3802 | 4 |
| PLX-4720 | C32 | 0.0032 | uM | 48 | hr | 2640 | 221 | 1.1770 | 1.1088 | 0.0837 | 0.0967 | 4 |
| SB590885 | C32 | 0.0032 | uM | 72 | hr | 3138 | 163 | 1.2989 | 1.0978 | 0.0519 | 0.0657 | 4 |
| SB590885 | C32 | 1.0000 | uM | 24 | hr | 1969 | 511 | 0.8430 | 0.8421 | 0.2595 | 0.2404 | 4 |
| SB590885 | C32 | 3.1600 | uM | 24 | hr | 1790 | 490 | 0.7516 | 0.7788 | 0.2737 | 0.2708 | 4 |
| PLX-4720 | C32 | 0.0032 | uM | 24 | hr | 1782 | 172 | 0.9308 | 0.9798 | 0.0965 | 0.0874 | 4 |
| SB590885 | C32 | 0.0316 | uM | 48 | hr | 2663 | 165 | 1.2155 | 1.0348 | 0.0620 | 0.0893 | 4 |
| SB590885 | C32 | 0.1000 | uM | 72 | hr | 2081 | 163 | 0.8374 | 0.7616 | 0.0783 | 0.0807 | 4 |
| SB590885 | C32 | 0.3160 | uM | 24 | hr | 2219 | 460 | 1.0170 | 0.9712 | 0.2073 | 0.2246 | 4 |
| SB590885 | C32 | 0.3160 | uM | 72 | hr | 1465 | 401 | 0.4646 | 0.4360 | 0.2737 | 0.2745 | 4 |
| SB590885 | C32 | 0.1000 | uM | 48 | hr | 2645 | 207 | 1.1863 | 1.0641 | 0.0783 | 0.0770 | 4 |
| SB590885 | C32 | 1.0000 | uM | 72 | hr | 1196 | 546 | 0.2838 | 0.2758 | 0.4565 | 0.4735 | 4 |
| SB590885 | C32 | 3.1600 | uM | 48 | hr | 1909 | 958 | 0.4627 | 0.3996 | 0.5018 | 0.5238 | 4 |
| SB590885 | C32 | 3.1600 | uM | 72 | hr | 990 | 497 | 0.2153 | 0.2092 | 0.5020 | 0.5417 | 4 |
| SB590885 | C32 | 0.0100 | uM | 24 | hr | 2109 | 263 | 1.0673 | 1.0475 | 0.1247 | 0.1377 | 4 |
| SB590885 | C32 | 0.0032 | uM | 48 | hr | 3034 | 191 | 1.3833 | 1.2035 | 0.0630 | 0.0832 | 4 |
| SB590885 | C32 | 0.0032 | uM | 24 | hr | 2049 | 142 | 1.1026 | 1.0722 | 0.0693 | 0.0901 | 4 |
| SB590885 | C32 | 0.1000 | uM | 24 | hr | 2245 | 400 | 1.0667 | 1.0512 | 0.1782 | 0.1944 | 4 |
| SB590885 | C32 | 0.0100 | uM | 48 | hr | 2691 | 296 | 1.1653 | 1.0390 | 0.1100 | 0.1215 | 4 |
| SB590885 | C32 | 0.0316 | uM | 24 | hr | 2215 | 342 | 1.0829 | 1.0901 | 0.1544 | 0.1588 | 4 |
| SB590885 | C32 | 0.0316 | uM | 72 | hr | 2544 | 90 | 1.0714 | 1.0834 | 0.0354 | 0.0299 | 4 |
| SB590885 | C32 | 0.3160 | uM | 48 | hr | 2415 | 412 | 0.9746 | 0.8577 | 0.1706 | 0.1894 | 4 |
| SB590885 | C32 | 0.0100 | uM | 72 | hr | 3021 | 158 | 1.2500 | 1.1912 | 0.0523 | 0.0532 | 4 |
| PLX-4720 | C32 | 0.0100 | uM | 24 | hr | 1975 | 233 | 1.0072 | 1.0031 | 0.1180 | 0.1207 | 4 |
| PLX-4720 | C32 | 0.0032 | uM | 72 | hr | 2525 | 221 | 1.0059 | 0.9573 | 0.0875 | 0.0846 | 4 |