Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | RVH-421 | 0.0032 | uM | 72 | hr | 8379 | 268 | 0.9294 | 0.9785 | 0.0320 | 0.0342 | 1 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 72 | hr | 8938 | 335 | 0.9858 | 0.9785 | 0.0375 | 0.0342 | 2 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 72 | hr | 8953 | 309 | 0.9905 | 0.9785 | 0.0345 | 0.0342 | 3 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 72 | hr | 9097 | 299 | 1.0082 | 0.9785 | 0.0329 | 0.0342 | 4 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 24 | hr | 1533 | 78 | 1.0526 | 1.0146 | 0.0509 | 0.0457 | 1 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 24 | hr | 1407 | 57 | 0.9766 | 1.0146 | 0.0405 | 0.0457 | 2 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | RVH-421 | 0.0100 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | RVH-421 | 0.0100 | uM | 48 | hr | 1720 | 122 | 0.8350 | 0.8813 | 0.0709 | 0.0620 | 1 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 48 | hr | 1542 | 104 | 0.7514 | 0.8813 | 0.0674 | 0.0620 | 2 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 48 | hr | 1907 | 92 | 0.9483 | 0.8813 | 0.0482 | 0.0620 | 3 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 48 | hr | 2020 | 124 | 0.9907 | 0.8813 | 0.0614 | 0.0620 | 4 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 72 | hr | 9239 | 359 | 1.0176 | 1.0312 | 0.0389 | 0.0350 | 1 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 72 | hr | 9529 | 333 | 1.0538 | 1.0312 | 0.0349 | 0.0350 | 2 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 72 | hr | 9105 | 306 | 1.0083 | 1.0312 | 0.0336 | 0.0350 | 3 |
| PLX-4720 | RVH-421 | 0.0100 | uM | 72 | hr | 9431 | 308 | 1.0454 | 1.0312 | 0.0327 | 0.0350 | 4 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 24 | hr | 1439 | 76 | 0.9860 | 0.9915 | 0.0528 | 0.0542 | 1 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 24 | hr | 1459 | 81 | 0.9969 | 0.9915 | 0.0555 | 0.0542 | 2 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | RVH-421 | 0.0316 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | RVH-421 | 0.0316 | uM | 48 | hr | 1907 | 94 | 0.9473 | 0.9481 | 0.0493 | 0.0512 | 1 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 48 | hr | 1684 | 104 | 0.8256 | 0.9481 | 0.0618 | 0.0512 | 2 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 48 | hr | 2159 | 100 | 1.0758 | 0.9481 | 0.0463 | 0.0512 | 3 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 48 | hr | 1896 | 90 | 0.9436 | 0.9481 | 0.0475 | 0.0512 | 4 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 72 | hr | 9190 | 336 | 1.0146 | 1.0084 | 0.0366 | 0.0338 | 1 |