Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | RVH-421 | 1.0000 | uM | 48 | hr | 1269 | 74 | 0.6244 | 0.6378 | 0.0583 | 0.0708 | 4 |
| SB590885 | RVH-421 | 1.0000 | uM | 72 | hr | 5672 | 227 | 0.6239 | 0.5748 | 0.0400 | 0.0371 | 1 |
| SB590885 | RVH-421 | 1.0000 | uM | 72 | hr | 5294 | 172 | 0.5869 | 0.5748 | 0.0325 | 0.0371 | 2 |
| SB590885 | RVH-421 | 1.0000 | uM | 72 | hr | 5023 | 199 | 0.5528 | 0.5748 | 0.0396 | 0.0371 | 3 |
| SB590885 | RVH-421 | 1.0000 | uM | 72 | hr | 4848 | 176 | 0.5354 | 0.5748 | 0.0363 | 0.0371 | 4 |
| SB590885 | RVH-421 | 3.1600 | uM | 24 | hr | 1338 | 73 | 0.9151 | 0.9285 | 0.0546 | 0.0619 | 1 |
| SB590885 | RVH-421 | 3.1600 | uM | 24 | hr | 1399 | 97 | 0.9419 | 0.9285 | 0.0693 | 0.0619 | 2 |
| SB590885 | RVH-421 | 3.1600 | uM | 24 | hr | 3 | ||||||
| SB590885 | RVH-421 | 3.1600 | uM | 24 | hr | 4 | ||||||
| SB590885 | RVH-421 | 3.1600 | uM | 48 | hr | 1152 | 114 | 0.5424 | 0.5132 | 0.0990 | 0.0883 | 1 |
| SB590885 | RVH-421 | 3.1600 | uM | 48 | hr | 1147 | 117 | 0.5382 | 0.5132 | 0.1020 | 0.0883 | 2 |
| SB590885 | RVH-421 | 3.1600 | uM | 48 | hr | 1019 | 73 | 0.4943 | 0.5132 | 0.0716 | 0.0883 | 3 |
| SB590885 | RVH-421 | 3.1600 | uM | 48 | hr | 995 | 80 | 0.4781 | 0.5132 | 0.0804 | 0.0883 | 4 |
| SB590885 | RVH-421 | 3.1600 | uM | 72 | hr | 4907 | 184 | 0.5412 | 0.5422 | 0.0375 | 0.0330 | 1 |
| SB590885 | RVH-421 | 3.1600 | uM | 72 | hr | 4803 | 180 | 0.5298 | 0.5422 | 0.0375 | 0.0330 | 2 |
| SB590885 | RVH-421 | 3.1600 | uM | 72 | hr | 4964 | 146 | 0.5521 | 0.5422 | 0.0294 | 0.0330 | 3 |
| SB590885 | RVH-421 | 3.1600 | uM | 72 | hr | 4899 | 135 | 0.5459 | 0.5422 | 0.0276 | 0.0330 | 4 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 24 | hr | 1455 | 83 | 0.9925 | 0.9321 | 0.0570 | 0.0586 | 1 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 24 | hr | 1282 | 77 | 0.8717 | 0.9321 | 0.0601 | 0.0586 | 2 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 24 | hr | 3 | ||||||
| PLX-4720 | RVH-421 | 0.0032 | uM | 24 | hr | 4 | ||||||
| PLX-4720 | RVH-421 | 0.0032 | uM | 48 | hr | 2325 | 113 | 1.1558 | 1.0326 | 0.0486 | 0.0464 | 1 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 48 | hr | 2067 | 104 | 1.0257 | 1.0326 | 0.0503 | 0.0464 | 2 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 48 | hr | 1919 | 73 | 0.9645 | 1.0326 | 0.0380 | 0.0464 | 3 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 48 | hr | 1980 | 96 | 0.9844 | 1.0326 | 0.0485 | 0.0464 | 4 |