JNK-IN-8 KiNativ -- single dose experiment - Dataset (ID:20213)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| JNK-IN-8 | A-375 | RSK1_domain1 | KVTRPDSGHLYAMkVLK | Lys1 | -13.2 | 1 | uM |
| JNK-IN-8 | A-375 | RSK1_domain2 | DLkPSNILYVDESGNPECLR | Lys2 | -6.6 | 1 | uM |
| JNK-IN-8 | A-375 | RSK2_domain1 | LTDFGLSkESIDHEKK | Activation Loop | -47.2 | 1 | uM |
| JNK-IN-8 | A-375 | RSK2_domain2 | TVEYLHAQGVVHRDLkPSNILYVDESGNPESIR | Lys2 | 32.6 | 1 | uM |
| JNK-IN-8 | A-375 | RSK2_domain2 | DLkPSNILYVDESGNPESIR | Lys2 | 10.7 | 1 | uM |
| JNK-IN-8 | A-375 | RSK2_domain2 | SkRDPTEEIEILLR | Protein Kinase Domain | -17.4 | 1 | uM |
| JNK-IN-8 | A-375 | RSK3_domain1 | DLkPENILLDEEGHIKITDFGLSK | Lys2 | -13.3 | 1 | uM |
| JNK-IN-8 | A-375 | RSKL1_domain1 | VLGVIDkVLLVMDTR | Protein Kinase Domain | -1.7 | 1 | uM |
| JNK-IN-8 | A-375 | SGK3 | FYAVkVLQK | Lys1 | -13.5 | 1 | uM |
| JNK-IN-8 | A-375 | SLK | AQNKETSVLAAAkVIDTK | Lys1 | -1.7 | 1 | uM |
| JNK-IN-8 | A-375 | SLK | DLkAGNILFTLDGDIKLADFGVSAK | Lys2 | 3.2 | 1 | uM |
| JNK-IN-8 | A-375 | SLK | IIHRDLkAGNILFTLDGDIK | Lys2 | -44.2 | 1 | uM |
| JNK-IN-8 | A-375 | SLK | DLkAGNILFTLDGDIK | Lys2 | 17.2 | 1 | uM |
| JNK-IN-8 | A-375 | SMG1 | DTVTIHSVGGTITILPTkTKPK | ATP | 18.3 | 1 | uM |
| JNK-IN-8 | A-375 | SRC | VAIkTLKPGTMSPEAFLQEAQVMKK | Lys1 | 1.2 | 1 | uM |
| JNK-IN-8 | A-375 | SRC | VAIkTLKPGTMSPEAFLQEAQVMK | Lys1 | 29.7 | 1 | uM |
| JNK-IN-8 | A-375 | STLK5 | YSVkVLPWLSPEVLQQNLQGYDAK | Activation Loop | 9.7 | 1 | uM |
| JNK-IN-8 | A-375 | TAO1,TAOK3 | DIkAGNILLTEPGQVK | Lys2 | 2.9 | 1 | uM |
| JNK-IN-8 | A-375 | TAOK2 | DVkAGNILLSEPGLVK | Lys2 | -21.6 | 1 | uM |
| JNK-IN-8 | A-375 | TBK1 | TGDLFAIkVFNNISFLRPVDVQMR | Lys1 | 5.7 | 1 | uM |
| JNK-IN-8 | A-375 | TLK1 | YLNEIKPPIIHYDLkPGNILLVDGTACGEIK | Lys2 | 2.6 | 1 | uM |
| JNK-IN-8 | A-375 | TLK2 | YVAVkIHQLNK | Lys1 | 2.0 | 1 | uM |
| JNK-IN-8 | A-375 | TYK2(Kin.Dom.2) | IGDFGLAkAVPEGHEYYR | Activation Loop | -3.9 | 1 | uM |
| JNK-IN-8 | A-375 | ULK3 | NISHLDLkPQNILLSSLEKPHLK | Lys2 | 32.3 | 1 | uM |
| JNK-IN-8 | A-375 | VRK2 | MLDVLEYIHENEYVHGDIkAANLLLGYK | Lys2 | 11.6 | 1 | uM |