CP-690550 KINOMEscan - Dataset (ID:20188)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Tofacitinib | JAK3(JH1domain-catalytic) | 0.2 | nM |
| Tofacitinib | JAK2(JH1domain-catalytic) | 0.6 | nM |
| Tofacitinib | JAK1(JH1domain-catalytic) | 1.6 | nM |
| Tofacitinib | TYK2(JH1domain-catalytic) | 4.8 | nM |
| Tofacitinib | DCAMKL3 | 12.0 | nM |
| Tofacitinib | TNK1 | 120.0 | nM |
| Tofacitinib | PKN1 | 170.0 | nM |
| Tofacitinib | SNARK | 240.0 | nM |
| Tofacitinib | ROCK2 | 420.0 | nM |
| Tofacitinib | LCK | 460.0 | nM |
| Tofacitinib | ROCK1 | 470.0 | nM |
| Tofacitinib | RSK4(Kin.Dom.2-C-terminal) | 540.0 | nM |
| Tofacitinib | LRRK2(G2019S) | 550.0 | nM |
| Tofacitinib | RSK3(Kin.Dom.2-C-terminal) | 600.0 | nM |
| Tofacitinib | FYN | 1100.0 | nM |
| Tofacitinib | DMPK | 1200.0 | nM |
| Tofacitinib | PKN2 | 1200.0 | nM |
| Tofacitinib | CAMK1 | 1200.0 | nM |
| Tofacitinib | LRRK2 | 1300.0 | nM |
| Tofacitinib | RSK1(Kin.Dom.2-C-terminal) | 1400.0 | nM |
| Tofacitinib | MKNK2 | 1600.0 | nM |
| Tofacitinib | CAMK1D | 1600.0 | nM |
| Tofacitinib | PKNB(M.tuberculosis) | 2000.0 | nM |
| Tofacitinib | KPCD | 2000.0 | nM |
| Tofacitinib | ABL1(T315I)-phosphorylated | 2200.0 | nM |