CP-690550 KINOMEscan - Dataset (ID:20188)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Tofacitinib | BIKE | 7100.0 | nM |
| Tofacitinib | DCLK1 | 6700.0 | nM |
| Tofacitinib | ABL1(H396P)-phosphorylated | 6700.0 | nM |
| Tofacitinib | ULK3 | 6400.0 | nM |
| Tofacitinib | MAP4K2 | 4800.0 | nM |
| Tofacitinib | ABL1(H396P)-nonphosphorylated | 4500.0 | nM |
| Tofacitinib | GRK7 | 4300.0 | nM |
| Tofacitinib | CAMK2A | 3500.0 | nM |
| Tofacitinib | RET(M918T) | 3300.0 | nM |
| Tofacitinib | KCC2D | 2700.0 | nM |
| Tofacitinib | ABL1(T315I)-phosphorylated | 2200.0 | nM |
| Tofacitinib | PKNB(M.tuberculosis) | 2000.0 | nM |
| Tofacitinib | KPCD | 2000.0 | nM |
| Tofacitinib | MKNK2 | 1600.0 | nM |
| Tofacitinib | CAMK1D | 1600.0 | nM |
| Tofacitinib | RSK1(Kin.Dom.2-C-terminal) | 1400.0 | nM |
| Tofacitinib | LRRK2 | 1300.0 | nM |
| Tofacitinib | CAMK1 | 1200.0 | nM |
| Tofacitinib | DMPK | 1200.0 | nM |
| Tofacitinib | PKN2 | 1200.0 | nM |
| Tofacitinib | FYN | 1100.0 | nM |
| Tofacitinib | RSK3(Kin.Dom.2-C-terminal) | 600.0 | nM |
| Tofacitinib | LRRK2(G2019S) | 550.0 | nM |
| Tofacitinib | RSK4(Kin.Dom.2-C-terminal) | 540.0 | nM |
| Tofacitinib | ROCK1 | 470.0 | nM |