CP-690550 KINOMEscan - Dataset - HMS LINCS Database

CP-690550 KINOMEscan - Dataset (ID:20188)

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Small molecules	Proteins

Small Molecule	Protein	Kd	Conc unit
Tofacitinib	ABL1(E255K)-phosphorylated		nM
Tofacitinib	ABL1(F317I)-nonphosphorylated		nM
Tofacitinib	ABL1(F317I)-phosphorylated		nM
Tofacitinib	ABL1(F317L)-nonphosphorylated		nM
Tofacitinib	ABL1(F317L)-phosphorylated		nM
Tofacitinib	ABL1(H396P)-nonphosphorylated	4500.0	nM
Tofacitinib	ABL1(H396P)-phosphorylated	6700.0	nM
Tofacitinib	ABL1(M351T)-phosphorylated		nM
Tofacitinib	ABL1(Q252H)-nonphosphorylated		nM
Tofacitinib	ABL1(Q252H)-phosphorylated		nM
Tofacitinib	ABL1(T315I)-nonphosphorylated		nM
Tofacitinib	ABL1(T315I)-phosphorylated	2200.0	nM
Tofacitinib	ABL1(Y253F)-phosphorylated		nM
Tofacitinib	ABL1-nonphosphorylated		nM
Tofacitinib	ABL1-phosphorylated		nM
Tofacitinib	ABL2		nM
Tofacitinib	ACVR1		nM
Tofacitinib	ACVR1B		nM
Tofacitinib	ACVR2A		nM
Tofacitinib	ACVR2B		nM
Tofacitinib	ACVRL1		nM
Tofacitinib	ADCK3		nM
Tofacitinib	ADCK4		nM
Tofacitinib	AKT1		nM
Tofacitinib	AAK1		nM