Basal profile of receptor tyrosine kinase signaling network measured by ELISA - Dataset (ID:20137)
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Cell Line | ERK (pg/cell) | Akt (pg/cell) | ErbB1 (pg/cell) | ErbB2 (pg/cell) | ErbB3 (pg/cell) | ErbB4 (pg/cell) | InsR (pg/cell) | IGF1R (pg/cell) | IGF2R (pg/cell) | VEGFR1 (pg/cell) | VEGFR2 (pg/cell) | VEGFR3 (pg/cell) | PDGFRa (pg/cell) | PDGFRb (pg/cell) | c-Met (pg/cell) | c-Kit (pg/cell) | EphA2 (pg/cell) | Src (pg/cell) | TrkA (pg/cell) | FGFR1 (pg/cell) | FGFR2 (pg/cell) | FGFR3 (pg/cell) | FGFR4 (pg/cell) | EpCAM (pg/cell) | pERK RnD (a.u.) | pERK CST (a.u.) | pAkt (a.u.) | pErbB1 (a.u.) | pErbB2 (a.u.) | pErbB3 (a.u.) | pErbB4 (a.u.) | pInsR (a.u.) | pIGF1R (a.u.) | pIGF1R (Y1131) (a.u.) | pVEGFR1 (a.u.) | pVEGFR2 (a.u.) | pVEGFR3 (a.u.) | pPDGFRa (a.u.) | pPDGFRb (a.u.) | pc-Met (a.u.) | pc-Kit (a.u.) | pEphA2 (a.u.) | pSrc (a.u.) | pTrkA (a.u.) | ER | PR |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HCC1500 | 0.001627 | 0.030076 | 0.008530 | 0.028522 | 0.021393 | 0.000533 | 0.013918 | 0.024088 | 0.044645 | 0.000527 | 0.000001 | 0.000193 | 0.000178 | 0.000462 | 0.000084 | 0.000000 | 0.000026 | 0.394097 | 0.000002 | 0.206517 | 0.003372 | 0.000565 | 0.000309 | 0.125318 | 0.000242 | 0.000234 | 0.004047 | 0.007146 | 0.010088 | 0.000052 | 0.002743 | 0.035367 | 0.002356 | 0.038419 | 0.000037 | 0.000013 | 0.000080 | 0.001452 | 0.000134 | 0.009774 | 0.001249 | 0.000023 | 0.000149 | 0.000895 | 0.004777 | 0.001929 |
MCF7 | 0.001550 | 0.127939 | 0.011460 | 0.023167 | 0.039686 | 0.000015 | 0.006522 | 0.074180 | 0.021787 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000158 | 0.013895 | 0.123345 | 0.000002 | 0.262003 | 0.000002 | 0.000018 | 0.000001 | 0.707886 | 0.000027 | 0.000407 | 0.033586 | 0.000014 | 0.002229 | 0.000052 | 0.000027 | 0.043588 | 0.000037 | 0.193246 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000023 | 0.000116 | 0.003922 | 0.002145 |
HCC1428 | 0.001057 | 0.075777 | 0.039530 | 0.038714 | 0.033628 | 0.001203 | 0.000061 | 0.024890 | 0.019215 | 0.000421 | 0.000001 | 0.000193 | 0.000178 | 0.000266 | 0.000084 | 0.000000 | 0.000837 | 1.543919 | 0.000002 | 0.176235 | 0.000002 | 0.000018 | 0.005277 | 0.166874 | 0.000109 | 0.000209 | 0.003641 | 0.014974 | 0.002229 | 0.000052 | 0.004321 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.004061 | 0.000080 | 0.000009 | 0.000134 | 0.003332 | 0.001249 | 0.000023 | 0.002004 | 0.000116 | 0.002332 | 0.001020 |
MDA-MB-134-VI | 0.001427 | 0.021843 | 0.001077 | 0.012026 | 0.017004 | 0.000015 | 0.000061 | 0.022199 | 0.017814 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000361 | 0.000084 | 0.000000 | 0.000832 | 0.130079 | 0.000002 | 0.183013 | 0.000002 | 0.000018 | 0.000001 | 0.106023 | 0.000072 | 0.002491 | 0.001641 | 0.000014 | 0.002229 | 0.000052 | 0.000027 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.001384 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000077 | 0.000116 | 0.001584 | 0.000079 |
CAMA-1 | 0.001036 | 0.016002 | 0.023685 | 0.063188 | 0.038498 | 0.002453 | 0.001774 | 0.005626 | 0.012643 | 0.000121 | 0.000001 | 0.000193 | 0.000178 | 0.000136 | 0.000084 | 0.000000 | 0.000750 | 0.057732 | 0.000002 | 0.126539 | 0.000002 | 0.000018 | 0.004167 | 0.073086 | 0.000027 | 0.000478 | 0.270453 | 0.000507 | 0.007421 | 0.000052 | 0.001415 | 0.019842 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000025 | 0.000116 | 0.001466 | 0.004511 |
T47D | 0.000537 | 0.031946 | 0.009859 | 0.035689 | 0.027587 | 0.000443 | 0.002633 | 0.023322 | 0.017964 | 0.000220 | 0.000001 | 0.000193 | 0.000178 | 0.000267 | 0.000084 | 0.000000 | 0.001839 | 0.284085 | 0.000002 | 0.196300 | 0.001170 | 0.000018 | 0.000001 | 0.166496 | 0.000225 | 0.000704 | 0.184693 | 0.003680 | 0.011140 | 0.000052 | 0.004440 | 0.005092 | 0.006041 | 0.026736 | 0.000037 | 0.000013 | 0.000080 | 0.001178 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000127 | 0.000116 | 0.001290 | 0.019619 |
MDA-MB-361 | 0.001199 | 0.067506 | 0.001650 | 0.209101 | 0.014416 | 0.000015 | 0.003542 | 0.015756 | 0.016276 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.001031 | 0.100950 | 0.000002 | 0.126329 | 0.001094 | 0.000018 | 0.000001 | 0.283766 | 0.000027 | 0.000755 | 0.056652 | 0.005513 | 0.076155 | 0.000052 | 0.000802 | 0.014004 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000705 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000106 | 0.000116 | 0.001168 | 0.001303 |
ZR-75-1 | 0.002113 | 0.103132 | 0.002349 | 0.059202 | 0.026874 | 0.000015 | 0.000061 | 0.012358 | 0.009299 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.003798 | 0.401987 | 0.000002 | 0.168463 | 0.000316 | 0.000203 | 0.000485 | 0.260343 | 0.000085 | 0.000293 | 0.037924 | 0.001668 | 0.005695 | 0.000052 | 0.000027 | 0.003005 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002378 | 0.000134 | 0.000016 | 0.001249 | 0.000182 | 0.000155 | 0.000116 | 0.001157 | 0.006319 |
BT-483 | 0.001683 | 0.039293 | 0.001949 | 0.201151 | 0.092377 | 0.000015 | 0.007435 | 0.095137 | 0.014937 | 0.000720 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.000026 | 4.809215 | 0.000002 | 0.326895 | 0.000002 | 0.000018 | 0.016574 | 0.419402 | 0.000027 | 0.000627 | 0.121213 | 0.003177 | 0.020875 | 0.000052 | 0.004336 | 0.058032 | 0.108322 | 0.075505 | 0.000037 | 0.000013 | 0.000080 | 0.002872 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.002324 | 0.000116 | 0.001073 | 0.000638 |
ZR-75-30 | 0.000961 | 0.079347 | 0.000084 | 2.054386 | 0.048846 | 0.000015 | 0.000061 | 0.007411 | 0.017689 | 0.000007 | 0.000001 | 0.000193 | 0.000605 | 0.000006 | 0.000084 | 0.000000 | 0.003164 | 0.221002 | 0.000002 | 0.194097 | 0.000002 | 0.001923 | 0.000145 | 0.057962 | 0.002051 | 0.004394 | 0.348622 | 0.002119 | 0.992071 | 0.020984 | 0.010718 | 0.022800 | 0.006964 | 0.001832 | 0.000037 | 0.000013 | 0.002139 | 0.001049 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000072 | 0.000116 | 0.000927 | 0.000116 |
MDA-MB-415 | 0.002446 | 0.033470 | 0.000084 | 0.052998 | 0.031361 | 0.000015 | 0.002611 | 0.004987 | 0.015992 | 0.000647 | 0.000001 | 0.000193 | 0.000178 | 0.000332 | 0.008883 | 0.004072 | 0.008449 | 3.594383 | 0.000002 | 0.231456 | 0.001831 | 0.000338 | 0.003574 | 0.522981 | 0.000027 | 0.000863 | 1.048483 | 0.003479 | 0.010413 | 0.000052 | 0.003052 | 0.038631 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002433 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000360 | 0.000116 | 0.000496 | 0.000401 |
UACC-812 | 0.002318 | 0.062712 | 0.003552 | 1.079578 | 0.011629 | 0.000015 | 0.000061 | 0.020988 | 0.030159 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.215155 | 0.000000 | 0.017181 | 1.395831 | 0.000002 | 0.292940 | 0.000132 | 0.000018 | 0.000001 | 0.268856 | 0.001274 | 0.006187 | 0.206463 | 0.016533 | 0.595025 | 0.000052 | 0.015995 | 0.000016 | 0.000037 | 0.109902 | 0.000037 | 0.000013 | 0.002079 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000628 | 0.000116 | 0.000341 | 0.000552 |
HCC1419 | 0.002537 | 0.068227 | 0.000084 | 3.032945 | 0.042585 | 0.000015 | 0.000061 | 0.005494 | 0.038255 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000331 | 0.000084 | 0.000000 | 0.019854 | 0.013025 | 0.000002 | 0.182028 | 0.000002 | 0.000288 | 0.001468 | 0.337559 | 0.000627 | 0.004841 | 0.566139 | 0.086873 | 2.431691 | 0.157330 | 0.273441 | 0.089457 | 0.056446 | 0.001832 | 0.000037 | 0.001134 | 0.005877 | 0.013438 | 0.000134 | 0.005253 | 0.001249 | 0.001041 | 0.000012 | 0.001878 | 0.000192 | 0.000120 |
UACC-893 | 0.001192 | 0.071233 | 0.055166 | 3.442462 | 0.021268 | 0.000015 | 0.004520 | 0.000206 | 0.062033 | 0.002080 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.023068 | 0.000000 | 0.010849 | 0.069885 | 0.000431 | 0.082970 | 0.004376 | 0.008224 | 0.002049 | 0.948209 | 0.001689 | 0.003509 | 1.943655 | 0.193576 | 2.123039 | 0.040024 | 0.041467 | 0.049085 | 0.021447 | 0.001832 | 0.000037 | 0.000013 | 0.001774 | 0.007064 | 0.000134 | 0.005683 | 0.001249 | 0.000023 | 0.000079 | 0.002605 | 0.000177 | 0.000433 |
MDA-MB-175-VII | 0.001428 | 0.047847 | 0.007853 | 0.074796 | 0.009289 | 0.000015 | 0.000061 | 0.007339 | 0.012638 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000000 | 0.014355 | 0.340263 | 0.000002 | 0.243260 | 0.000002 | 0.000018 | 0.000001 | 0.044485 | 0.000851 | 0.008435 | 0.296530 | 0.000541 | 0.015937 | 0.009106 | 0.008008 | 0.006831 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000375 | 0.000116 | 0.000090 | 0.000047 |
HCC202 | 0.002293 | 0.083788 | 0.066754 | 0.935180 | 0.020796 | 0.000015 | 0.007420 | 0.003045 | 0.013029 | 0.000474 | 0.000001 | 0.000193 | 0.000178 | 0.000346 | 0.000084 | 0.000000 | 0.037725 | 0.250326 | 0.000002 | 0.264042 | 0.004160 | 0.000355 | 0.000253 | 0.991954 | 0.000945 | 0.007669 | 0.437659 | 0.038539 | 0.193317 | 0.000052 | 0.009899 | 0.019944 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000188 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000134 | 0.000116 | 0.000077 | 0.000228 |
HCC1937 | 0.001734 | 0.023106 | 0.126316 | 0.023936 | 0.002304 | 0.000015 | 0.002695 | 0.001929 | 0.009279 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.199776 | 0.000000 | 0.135122 | 0.133118 | 0.000002 | 0.225204 | 0.000308 | 0.000847 | 0.000001 | 0.524161 | 0.000027 | 0.002131 | 0.296125 | 0.005225 | 0.002229 | 0.000052 | 0.005032 | 0.029760 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000120 | 0.000116 | 0.000072 | 0.000120 |
HCC1569 | 0.001239 | 0.025774 | 0.008103 | 1.209554 | 0.023939 | 0.000015 | 0.000061 | 0.063655 | 0.021025 | 0.000193 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.042288 | 0.000000 | 0.011558 | 1.525413 | 0.000002 | 0.217837 | 0.000745 | 0.000988 | 0.000001 | 0.107529 | 0.000572 | 0.000384 | 0.376618 | 0.014228 | 0.468610 | 0.000647 | 0.003379 | 0.003545 | 0.005121 | 0.001832 | 0.000037 | 0.000013 | 0.000399 | 0.000009 | 0.000134 | 0.002549 | 0.001249 | 0.000023 | 0.000337 | 0.000116 | 0.000060 | 0.000253 |
HCC1187 | 0.001231 | 0.067625 | 0.078729 | 0.041583 | 0.003479 | 0.000015 | 0.011093 | 0.000584 | 0.052908 | 0.000770 | 0.001859 | 0.000193 | 0.000393 | 0.000289 | 0.000084 | 0.018901 | 0.003747 | 0.287014 | 0.000002 | 0.279688 | 0.000459 | 0.000018 | 0.000001 | 0.158536 | 0.000156 | 0.000638 | 0.249109 | 0.010311 | 0.015487 | 0.000052 | 0.001503 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.011705 | 0.000080 | 0.001174 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000065 | 0.000116 | 0.000059 | 0.000147 |
MDA-MB-453 | 0.001429 | 0.120120 | 0.002807 | 0.247025 | 0.028565 | 0.000015 | 0.005737 | 0.002220 | 0.011964 | 0.000480 | 0.000001 | 0.000193 | 0.000178 | 0.000130 | 0.000084 | 0.000028 | 0.001600 | 0.000100 | 0.000002 | 0.263671 | 0.001494 | 0.000018 | 0.065669 | 0.382461 | 0.000189 | 0.002063 | 0.506361 | 0.007798 | 0.095964 | 0.007578 | 0.009805 | 0.016826 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.002579 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000023 | 0.000116 | 0.000059 | 0.000160 |
BT-474 | 0.001056 | 0.059340 | 0.006800 | 1.057178 | 0.026343 | 0.000015 | 0.002525 | 0.015606 | 0.018435 | 0.000642 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.003289 | 0.000000 | 0.001834 | 0.013513 | 0.000002 | 0.178006 | 0.001725 | 0.000655 | 0.002142 | 0.099904 | 0.000170 | 0.000673 | 0.226103 | 0.124231 | 0.992579 | 0.064679 | 0.025341 | 0.033362 | 0.013541 | 0.001832 | 0.000037 | 0.000013 | 0.003374 | 0.005482 | 0.000134 | 0.000822 | 0.001249 | 0.000023 | 0.000023 | 0.000652 | 0.000058 | 0.000057 |
MCF12A | 0.000301 | 0.016529 | 0.189237 | 0.008829 | 0.001731 | 0.000015 | 0.000061 | 0.013479 | 0.009227 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.510546 | 0.000000 | 0.017256 | 0.092326 | 0.000002 | 0.100947 | 0.000002 | 0.000018 | 0.000001 | 0.058942 | 0.000027 | 0.000134 | 0.017063 | 0.195698 | 0.002618 | 0.000052 | 0.000724 | 0.015404 | 0.010887 | 0.050437 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.009245 | 0.001249 | 0.000110 | 0.000256 | 0.000116 | 0.000058 | 0.000021 |
HCC38 | 0.001650 | 0.030563 | 0.040007 | 0.041302 | 0.024356 | 0.000015 | 0.001698 | 0.013109 | 0.015090 | 0.000145 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.011841 | 0.002042 | 0.072876 | 0.280569 | 0.000002 | 0.260344 | 0.001299 | 0.000018 | 0.000001 | 0.763470 | 0.000257 | 0.000854 | 0.077133 | 0.008259 | 0.008386 | 0.000052 | 0.005543 | 0.001929 | 0.005388 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000137 | 0.000116 | 0.000053 | 0.000133 |
MDA-MB-468 | 0.000581 | 0.018362 | 0.896891 | 0.000084 | 0.003846 | 0.002097 | 0.006354 | 0.003904 | 0.006148 | 0.000257 | 0.000409 | 0.000193 | 0.000178 | 0.000246 | 0.175679 | 0.000140 | 0.008254 | 0.089507 | 0.000002 | 0.158480 | 0.000157 | 0.000018 | 0.000001 | 0.570714 | 0.000096 | 0.000599 | 0.270148 | 0.172730 | 0.005938 | 0.000052 | 0.004697 | 0.013372 | 0.002274 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.001538 | 0.000134 | 0.000316 | 0.001249 | 0.000023 | 0.000077 | 0.005793 | 0.000048 | 0.000109 |
BT-549 | 0.001734 | 0.028424 | 0.139275 | 0.011181 | 0.000070 | 0.000015 | 0.000061 | 0.005810 | 0.076807 | 0.000499 | 0.000001 | 0.000193 | 0.000497 | 0.000150 | 0.302179 | 0.000000 | 0.286646 | 0.294228 | 0.000002 | 0.294733 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000476 | 0.002044 | 0.303062 | 0.016341 | 0.012222 | 0.000052 | 0.014529 | 0.007478 | 0.005798 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.004543 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000203 | 0.000116 | 0.000041 | 0.000118 |