HMS LINCS Project

Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)

• Detail
• Small Molecules Studied
• Cell Lines Studied
• Data Columns
• Results

 Full screen view

Download: Excel (XLSX), Comma-separated (CSV)

Filter results: >>>>

<<<<

Select the entities to show:

Small molecules	Cells
10057:MK2206 10098:Gefitinib 10172:GSK1059615 10232:Dactolisib 10280:Triciribine 10345:Torkinib	50091:AU565 50213:HCC1954 50541:T47D 50583:MCF 10A

Search Clear Form

• |<
• <<
• Previous
• Page 9 of 116
• Next
• >>
• >
• 201 to 225 of 2880 records
• per page:25501002501000

Small Molecule	Cell Line	Drug Concentration	Conc Units	Timepoint	Timepoint Units	Measured pERK (Alexa 488)	Measured p-Rb (Alexa 568)	Alexa Fluor 647	Measured p-Akt/p-4EBP1/p-S6 (Alexa 647)	Image
Triciribine	AU565	31.6	nM	6	hr	220.69	55.70	p-Akt	17.86
Triciribine	AU565	31.6	nM	24	hr	470.63	111.42	p-Akt	80.32
Dactolisib	AU565	31.6	nM	6	hr	227.70	45.24	p-Akt	16.61
Dactolisib	AU565	31.6	nM	24	hr	380.97	70.29	p-Akt	48.32
Gefitinib	HCC1954	31.6	nM	6	hr	154.47	31.92	p-Akt	21.41
Gefitinib	HCC1954	31.6	nM	24	hr	266.54	116.41	p-Akt	79.02
Torkinib	HCC1954	7.5	nM	6	hr	166.69	28.86	p-Akt	16.56
Torkinib	HCC1954	7.5	nM	24	hr	251.11	94.12	p-Akt	46.29
GSK1059615	HCC1954	31.6	nM	6	hr	360.63	99.54	p-Akt	54.35
GSK1059615	HCC1954	31.6	nM	24	hr	290.96	105.96	p-Akt	57.79
MK2206	HCC1954	31.6	nM	6	hr	155.55	39.66	p-Akt	15.51
MK2206	HCC1954	31.6	nM	24	hr	253.49	107.70	p-Akt	36.28
Triciribine	HCC1954	31.6	nM	6	hr	227.75	83.99	p-Akt	41.27
Triciribine	HCC1954	31.6	nM	24	hr	272.86	101.09	p-Akt	49.02
Dactolisib	HCC1954	31.6	nM	6	hr	236.72	75.54	p-Akt	26.13
Dactolisib	HCC1954	31.6	nM	24	hr	279.67	87.04	p-Akt	38.76
Gefitinib	MCF 10A	31.6	nM	6	hr	398.27	164.91	p-Akt	40.24
Gefitinib	MCF 10A	31.6	nM	24	hr	238.72	124.65	p-Akt	33.96
Torkinib	MCF 10A	7.5	nM	6	hr	427.52	157.79	p-Akt	37.03
Torkinib	MCF 10A	7.5	nM	24	hr	366.02	147.83	p-Akt	35.28
GSK1059615	MCF 10A	31.6	nM	6	hr	373.13	166.27	p-Akt	34.46
GSK1059615	MCF 10A	31.6	nM	24	hr	339.47	139.37	p-Akt	33.88
MK2206	MCF 10A	31.6	nM	6	hr	380.25	159.60	p-Akt	30.86
MK2206	MCF 10A	31.6	nM	24	hr	281.68	141.57	p-Akt	26.79
Triciribine	MCF 10A	31.6	nM	6	hr	381.96	160.49	p-Akt	30.98

• |<
• <<
• Previous
• Page 9 of 116
• Next
• >>
• >
• 201 to 225 of 2880 records
• per page:25501002501000

• • HMS LINCS DB home
  • Small molecules
  • Structure search
  • Salt table
  • Cells
  • Cell Lines
  • Primary Cells
  • iPSCs
  • Embryonic Stem Cells
  • Differentiated Cells
  • Proteins
  • Antibodies
  • Other Reagents
  • Unclassified Perturbagens
  • Datasets
  • Libraries
  • Login