HMS LINCS Project

Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)

• Detail
• Small Molecules Studied
• Cell Lines Studied
• Data Columns
• Results

 Full screen view

Download: Excel (XLSX), Comma-separated (CSV)

Filter results: >>>>

<<<<

Select the entities to show:

Small molecules	Cells
10057:MK2206 10098:Gefitinib 10172:GSK1059615 10232:Dactolisib 10280:Triciribine 10345:Torkinib	50091:AU565 50213:HCC1954 50541:T47D 50583:MCF 10A

Search Clear Form

• |<
• <<
• Previous
• Page 6 of 116
• Next
• >>
• >
• 126 to 150 of 2880 records
• per page:25501002501000

Small Molecule	Cell Line	Drug Concentration	Conc Units	Timepoint	Timepoint Units	Measured pERK (Alexa 488)	Measured p-Rb (Alexa 568)	Alexa Fluor 647	Measured p-Akt/p-4EBP1/p-S6 (Alexa 647)	Image
GSK1059615	MCF 10A	3.16	nM	24	hr	367.96	143.08	p-Akt	41.13
MK2206	MCF 10A	3.16	nM	6	hr	401.94	154.74	p-Akt	43.87
MK2206	MCF 10A	3.16	nM	24	hr	313.82	137.95	p-Akt	41.12
Triciribine	MCF 10A	3.16	nM	6	hr	404.45	155.90	p-Akt	44.15
Triciribine	MCF 10A	3.16	nM	24	hr	272.12	127.39	p-Akt	34.72
Dactolisib	MCF 10A	3.16	nM	6	hr	394.32	173.00	p-Akt	43.59
Dactolisib	MCF 10A	3.16	nM	24	hr	306.83	142.69	p-Akt	34.75
Gefitinib	T47D	3.16	nM	6	hr	181.54	100.89	p-Akt	103.21
Gefitinib	T47D	3.16	nM	24	hr	164.50	108.71	p-Akt	78.14
Torkinib	T47D	0.422	nM	6	hr	170.81	90.25	p-Akt	78.90
Torkinib	T47D	0.422	nM	24	hr	165.87	94.49	p-Akt	59.39
GSK1059615	T47D	3.16	nM	6	hr	165.75	87.48	p-Akt	92.56
GSK1059615	T47D	3.16	nM	24	hr	161.44	94.40	p-Akt	65.08
MK2206	T47D	3.16	nM	6	hr	101.19	50.29	p-Akt	14.05
MK2206	T47D	3.16	nM	24	hr	161.28	93.73	p-Akt	49.64
Triciribine	T47D	3.16	nM	6	hr	96.97	52.42	p-Akt	20.09
Triciribine	T47D	3.16	nM	24	hr	157.47	91.95	p-Akt	63.67
Dactolisib	T47D	3.16	nM	6	hr	112.31	65.77	p-Akt	19.14
Dactolisib	T47D	3.16	nM	24	hr	138.41	87.20	p-Akt	40.75
Gefitinib	AU565	10.0	nM	6	hr	241.48	51.68	p-Akt	25.73
Gefitinib	AU565	10.0	nM	24	hr	525.48	125.00	p-Akt	138.40
Torkinib	AU565	1.78	nM	6	hr	231.62	48.81	p-Akt	18.34
Torkinib	AU565	1.78	nM	24	hr	442.08	102.06	p-Akt	74.88
GSK1059615	AU565	10.0	nM	6	hr	218.56	55.54	p-Akt	24.76
GSK1059615	AU565	10.0	nM	24	hr	440.93	111.08	p-Akt	88.89

• |<
• <<
• Previous
• Page 6 of 116
• Next
• >>
• >
• 126 to 150 of 2880 records
• per page:25501002501000

• • HMS LINCS DB home
  • Small molecules
  • Structure search
  • Salt table
  • Cells
  • Cell Lines
  • Primary Cells
  • iPSCs
  • Embryonic Stem Cells
  • Differentiated Cells
  • Proteins
  • Antibodies
  • Other Reagents
  • Unclassified Perturbagens
  • Datasets
  • Libraries
  • Login