Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Olomoucine II | MDA-MB-157 | -3.8761 | 0.9806 | -5.1231 | -5.0940 | -5.1873 | 4.0000 | 0.1158 | 0.1158 | 7.1629 |
| Olomoucine II | MDA-MB-175-VII | -3.8761 | 0.8500 | -5.2521 | -3.8761 | -5.2061 | 1.7370 | 0.6378 | 0.6389 | 7.8579 |
| Olomoucine II | MDA-MB-361 | -3.8761 | 0.9173 | -4.9241 | -4.6548 | -5.0056 | 3.2605 | 0.4181 | 0.4187 | 7.8896 |
| Olomoucine II | MDA-MB-436 | -3.8761 | 0.9077 | -5.1451 | -4.9031 | -5.1513 | 3.9990 | 0.4462 | 0.4462 | 8.1066 |
| Olomoucine II | MDA-MB-453 | -3.8761 | 0.9528 | -5.1421 | -5.1414 | -5.3057 | 2.6170 | 0.0010 | 0.0015 | 6.4299 |
| Olomoucine II | MDA-MB-468 | -3.8761 | 0.8992 | -5.1881 | -5.1814 | -5.2342 | 4.0000 | 0.0302 | 0.0302 | 7.3947 |
| Olomoucine II | T47D | -3.8761 | 0.8965 | -5.2601 | -4.9914 | -5.1964 | 3.9950 | 0.4577 | 0.4577 | 7.5462 |
| Olomoucine II | UACC-812 | -3.8761 | 0.9020 | -5.0921 | -4.9695 | -5.1718 | 3.8285 | 0.2289 | 0.2289 | 7.0809 |
| Olomoucine II | UACC-893 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Olomoucine II | ZR-75-1 | -3.8761 | 0.8685 | -5.0511 | -4.9190 | -5.0945 | 3.9950 | 0.3513 | 0.3513 | 7.2588 |
| Olomoucine II | 184B5 | -3.8761 | 0.9593 | -5.3501 | -5.2549 | -5.5534 | 1.0770 | 0.1049 | 0.1275 | 6.8015 |
| Olomoucine II | HCC1187 | -3.8761 | 0.9860 | -5.0731 | -5.0708 | -5.2124 | 2.7620 | 0.0058 | 0.0063 | 6.8131 |
| Olomoucine II | MCF 10A | -3.8761 | 0.9673 | -5.4931 | -5.4893 | -5.5327 | 2.9600 | 0.0118 | 0.0118 | 6.4850 |
| Olomoucine II | MCF 10F | -3.8761 | 0.9459 | -5.0001 | -4.9869 | -5.0822 | 3.6880 | 0.0522 | 0.0523 | 7.5056 |
| Olomoucine II | SUM1315MO2 | -3.8761 | 0.9897 | -5.2001 | -5.1819 | -5.4151 | 2.7020 | 0.0541 | 0.0544 | 6.8308 |
| Olomoucine II | SUM149PT | -3.8761 | 0.9717 | -5.1561 | -5.1557 | -5.2203 | 2.9865 | 0.0023 | 0.0030 | 6.6727 |
| Olomoucine II | SUM159PT | -3.8761 | 0.9612 | -5.3431 | -5.3098 | -5.3451 | 1.6530 | 0.0592 | 0.0627 | 6.2921 |
| Olomoucine II | SUM185PE | -3.8761 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.9046 |
| Olomoucine II | SUM225CWN | -3.8761 | 0.8271 | -5.2531 | -5.1291 | -5.2857 | 3.9840 | 0.3391 | 0.3391 | 7.3367 |
| Olomoucine II | SUM229PE | -3.8761 | 0.9367 | -5.1271 | -5.0133 | -5.1182 | 2.6860 | 0.2529 | 0.2532 | 7.2427 |
| Olomoucine II | SUM52PE | -3.8761 | 0.8862 | -5.1586 | -4.8561 | -5.2355 | 1.1565 | 0.2759 | 0.2993 | 7.2479 |
| Olomoucine II | 184A1 | -3.8761 | 0.9406 | -5.4031 | -5.2740 | -5.4786 | 2.6220 | 0.2714 | 0.2715 | 7.4802 |
| Olomoucine II | MCF12A | -3.8761 | 0.9818 | -5.1771 | -5.1151 | -5.2151 | 4.0000 | 0.2187 | 0.2187 | 7.5887 |
| Olomoucine II | MX1 | -3.8761 | 0.9589 | -5.0991 | -5.0973 | -5.2469 | 2.4920 | 0.0000 | 0.0064 | 7.0652 |
| Olomoucine II | T47DKBLUC | -3.8761 | 0.8823 | -5.1011 | -3.8761 | -5.0389 | 3.9990 | 0.5359 | 0.5359 | 7.6766 |