Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Trichostatin A | SUM225CWN | -2.3010 | 0.9824 | -4.6735 | -4.6603 | -4.8936 | 2.2205 | 0.0299 | 0.0301 | 5.2381 |
| Trichostatin A | SUM229PE | -2.3010 | 0.9820 | -4.7270 | -4.7202 | -4.8837 | 2.4200 | 0.0192 | 0.0192 | 5.0419 |
| Trichostatin A | SUM52PE | -2.3010 | 0.9394 | -5.4220 | -5.4112 | -5.6493 | 1.5135 | 0.0198 | 0.0198 | 4.0655 |
| Trichostatin A | 184A1 | -2.3010 | 0.9665 | -4.4785 | -4.4657 | -4.7341 | 1.2225 | 0.0173 | 0.0194 | 5.6423 |
| Trichostatin A | MCF12A | -2.3010 | 0.9877 | -4.6640 | -4.6507 | -4.7526 | 1.5750 | 0.0240 | 0.0242 | 5.2011 |
| Trichostatin A | MX1 | -2.3010 | 0.9903 | -4.4800 | -4.4634 | -4.7871 | 1.8440 | 0.0332 | 0.0333 | 5.6594 |
| Trichostatin A | T47DKBLUC | -2.3010 | 0.9845 | -5.1270 | -5.1211 | -5.3735 | 1.7930 | 0.0111 | 0.0113 | 4.3892 |
| Trichostatin A | 600MPE | -2.3010 | 0.9781 | -4.7385 | -4.7348 | -5.1894 | 1.3262 | 0.0061 | 0.0087 | 4.8220 |
| Trichostatin A | HCC2185 | -2.3010 | 0.9910 | -4.6010 | -4.5958 | -4.8275 | 3.2570 | 0.0153 | 0.0153 | 5.2562 |
| Trichostatin A | HCC3153 | -2.3010 | 0.9928 | -4.4800 | -4.4611 | -4.6533 | 2.0190 | 0.0728 | 0.0731 | 5.6299 |
| Trichostatin A | LY2 | -2.3010 | 0.9785 | -4.7670 | -4.7587 | -4.8913 | 2.4760 | 0.0223 | 0.0223 | 5.3241 |
| Trichostatin A | ZR75B | -2.3010 | 0.9827 | -5.1260 | -5.0946 | -5.3275 | 1.1750 | 0.0408 | 0.0413 | 4.5727 |
| Triciribine | MCF7 | -4.4776 | 0.9691 | -6.5801 | -6.1686 | -6.7767 | 0.8491 | 0.2748 | 0.2866 | 6.4195 |
| Triciribine | SK-BR-3 | -4.4776 | 0.9794 | -7.1261 | -7.0205 | -7.3056 | 1.0085 | 0.1086 | 0.1106 | 5.1406 |
| Triciribine | MDA-MB-231 | -4.4776 | 0.7777 | -5.9048 | -4.9232 | -5.2626 | 0.7320 | 0.3927 | 0.4692 | 8.3898 |
| Triciribine | AU565 | -4.4776 | 0.9816 | -7.3716 | -7.3323 | -7.6135 | 0.7532 | 0.0324 | 0.0389 | 4.5358 |
| Triciribine | BT-20 | -4.4776 | 0.9563 | -5.5436 | -5.2117 | -6.0030 | 0.7149 | 0.1791 | 0.3001 | 7.3224 |
| Triciribine | BT-474 | -4.4776 | 0.8889 | -6.7916 | -5.8680 | -7.0645 | 0.7845 | 0.4058 | 0.4148 | 6.8088 |
| Triciribine | BT-483 | -4.4776 | 0.8148 | -6.4496 | -4.4776 | -7.6168 | 0.3389 | 0.4704 | 0.5640 | 7.1257 |
| Triciribine | BT-549 | -4.4776 | 0.8695 | -5.4856 | -4.4776 | -4.5806 | 0.7227 | 0.4548 | 0.5406 | 7.8425 |
| Triciribine | CAMA-1 | -4.4776 | 0.8651 | -5.3606 | -4.4776 | -5.7331 | 0.4620 | 0.4116 | 0.5770 | 7.3674 |
| Triciribine | HCC1143 | -4.4776 | 0.9159 | -4.9695 | -4.9694 | -5.6388 | 0.4002 | 0.0000 | 0.3886 | 7.1918 |
| Triciribine | HCC1395 | -4.4776 | 0.8151 | -4.3237 | -4.4776 | -5.8158 | 0.2974 | 0.1533 | 0.5989 | 7.6593 |
| Triciribine | HCC1419 | -4.4776 | 0.8884 | -5.0431 | -4.4776 | -6.6517 | 0.5086 | 0.2758 | 0.5662 | 7.7476 |
| Triciribine | HCC1428 | -4.4776 | 0.9804 | -5.8886 | -5.8680 | -7.0873 | 0.4599 | 0.0000 | 0.1972 | 6.2826 |