Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Docetaxel | BT-474 | -5.0000 | 0.9632 | -8.1135 | -7.6341 | -8.2251 | 2.1630 | 0.4053 | 0.4053 | 6.0804 |
| Docetaxel | HCC1143 | -5.0000 | 0.9068 | -7.9820 | -7.6856 | -8.0792 | 2.5470 | 0.3678 | 0.3679 | 6.0751 |
| Docetaxel | BT-483 | -5.0000 | 0.7596 | -7.6580 | -5.0000 | -7.5839 | 1.6960 | 0.7542 | 0.7542 | 8.0907 |
| Docetaxel | BT-549 | -5.0000 | 0.9751 | -8.5540 | -8.3753 | -8.5191 | 1.7370 | 0.2542 | 0.2542 | 4.8575 |
| Docetaxel | HCC1419 | -5.0000 | 0.7471 | -7.7670 | -5.0000 | -7.8886 | 1.6530 | 0.7057 | 0.7057 | 8.4471 |
| Docetaxel | HCC1428 | -5.0000 | 0.8405 | -8.0940 | -5.0000 | -6.4032 | 1.0855 | 0.7934 | 0.7935 | 8.4257 |
| Docetaxel | HCC1806 | -5.0000 | 0.9937 | -8.5945 | -8.5659 | -8.6584 | 2.1230 | 0.0853 | 0.0853 | 3.8338 |
| Docetaxel | HCC1937 | -5.0000 | 0.9371 | -8.2330 | -5.0000 | -8.2189 | 3.9980 | 0.6654 | 0.6654 | 7.3654 |
| Docetaxel | HCC38 | -5.0000 | 0.9818 | -8.6120 | -8.4709 | -8.7384 | 1.9535 | 0.2238 | 0.2238 | 4.5902 |
| Docetaxel | HCC70 | -5.0000 | 0.9713 | -8.1680 | -7.8487 | -8.5185 | 1.5350 | 0.2799 | 0.2799 | 5.4623 |
| Docetaxel | MDA-MB-134-VI | -5.0000 | 0.9854 | -8.1760 | -7.8585 | -8.2672 | 1.6740 | 0.3530 | 0.3530 | 7.8615 |
| Docetaxel | MDA-MB-175-VII | -5.0000 | 0.8165 | -8.0975 | -5.0000 | -7.8058 | 2.7620 | 0.7630 | 0.7630 | 7.7847 |
| Docetaxel | MCF7 | -5.0000 | 0.9618 | -8.0690 | -6.8236 | -7.9760 | 1.1040 | 0.4827 | 0.4828 | 6.4719 |
| Docetaxel | HCC1395 | -5.0000 | 0.8432 | -8.1310 | -7.8841 | -8.3044 | 2.0065 | 0.3383 | 0.3383 | 5.8332 |
| Docetaxel | SK-BR-3 | -5.0000 | 0.9657 | -7.8975 | -7.8099 | -8.0272 | 2.7945 | 0.2183 | 0.2183 | 5.3521 |
| Docetaxel | MDA-MB-468 | -5.0000 | 0.9839 | -8.5860 | -8.5206 | -8.7081 | 1.8710 | 0.0837 | 0.0837 | 3.8228 |
| Docetaxel | ZR75B | -5.0000 | 0.9309 | -8.2560 | -5.0000 | -7.9688 | 2.3085 | 0.6759 | 0.6759 | 7.3742 |
| Docetaxel | HCC3153 | -5.0000 | 0.9655 | -7.8850 | -7.4961 | -8.0029 | 1.5310 | 0.4040 | 0.4040 | 6.2205 |
| Docetaxel | T47DKBLUC | -5.0000 | 0.9620 | -7.7980 | -7.3631 | -7.9166 | 1.9650 | 0.4303 | 0.4303 | 6.4961 |
| Docetaxel | MCF12A | -5.0000 | 0.9298 | -8.6260 | -8.2368 | -8.6178 | 1.3250 | 0.3435 | 0.3436 | 5.1394 |
| Docetaxel | 600MPE | -5.0000 | 0.7992 | -7.6820 | -5.0000 | -7.1151 | 2.4180 | 0.7415 | 0.7415 | 8.2414 |
| Docetaxel | LY2 | -5.0000 | 0.9638 | -8.2275 | -7.2971 | -8.2340 | 1.5105 | 0.3819 | 0.3819 | 5.9691 |
| Docetaxel | HCC2185 | -5.0000 | 0.8601 | -8.4610 | -5.0000 | -8.5299 | 2.8345 | 0.6559 | 0.6559 | 7.0951 |
| Docetaxel | SUM185PE | -5.0000 | 0.9052 | -7.7910 | -5.0000 | -7.7962 | 3.9920 | 0.5991 | 0.5991 | 7.6798 |
| Docetaxel | SUM159PT | -5.0000 | 0.9753 | -8.7915 | -8.7477 | -8.8094 | 2.1380 | 0.0956 | 0.0956 | 3.6627 |