Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Doxorubicin | HCC38 | -6.2596 | 0.8958 | -7.5606 | -7.5605 | -8.1413 | 1.5120 | 0.0000 | 0.0107 | 6.2784 |
| Doxorubicin | HCC202 | -6.2596 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.7283 |
| Doxorubicin | HCC1954 | -6.2596 | 0.9153 | -6.9711 | -6.9712 | -7.1988 | 0.7182 | 0.0000 | 0.2357 | 7.0541 |
| Doxorubicin | HCC1937 | -6.2596 | 0.8638 | -5.8318 | -6.2596 | -6.6820 | 0.8216 | 0.0000 | 0.6920 | 8.5936 |
| Doxorubicin | HCC1806 | -6.2596 | 0.9360 | -6.9901 | -6.9901 | -7.3056 | 1.2590 | 0.0000 | 0.1493 | 7.3923 |
| Doxorubicin | SUM149PT | -6.2596 | 0.7836 | -6.6004 | -6.6004 | -6.7222 | 2.5000 | 0.0000 | 0.1233 | 7.8025 |
| Doxorubicin | T47DKBLUC | -6.2596 | 0.8382 | -6.6518 | -6.2596 | -7.0234 | 1.2130 | 0.5184 | 0.5374 | 8.2598 |
| Doxorubicin | SUM229PE | -6.2596 | 0.8997 | -6.5291 | -6.5291 | -6.6895 | 1.2090 | 0.0000 | 0.3208 | 7.7006 |
| Doxorubicin | 600MPE | -6.2596 | 0.9428 | -6.5567 | -6.5568 | -6.6508 | 2.0470 | 0.0000 | 0.1977 | 7.8129 |
| Doxorubicin | HCC1428 | -6.2596 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.8373 |
| Doxorubicin | HCC1569 | -6.2596 | 0.8574 | -5.6508 | -6.2596 | -6.4796 | 0.4280 | 0.0000 | 0.6457 | 8.1424 |
| Doxorubicin | MCF7 | -6.2596 | 0.9750 | -6.7234 | -6.7235 | -6.9475 | 1.3200 | 0.0000 | 0.1963 | 7.9183 |
| Doxorubicin | SK-BR-3 | -6.2596 | 0.9787 | -6.9014 | -6.8981 | -7.1294 | 1.4280 | 0.0056 | 0.1131 | 7.3714 |
| Doxorubicin | MDA-MB-231 | -6.2596 | 0.9375 | -7.2786 | -7.2786 | -7.4049 | 0.8349 | 0.0000 | 0.1236 | 6.8415 |
| Doxorubicin | AU565 | -6.2596 | 0.9064 | -7.2888 | -7.2496 | -7.4293 | 1.8740 | 0.0680 | 0.0814 | 7.0531 |
| Doxorubicin | BT-20 | -6.2596 | 0.9277 | -6.3089 | -6.3089 | -6.5270 | 2.3340 | 0.0000 | 0.4342 | 8.2808 |
| Doxorubicin | MCF 10F | -6.2596 | 0.8259 | -5.7006 | -6.2596 | -6.4169 | 0.4388 | 0.1948 | 0.7082 | 8.3091 |
| Doxorubicin | SUM1315MO2 | -6.2596 | 0.8846 | -7.4776 | -6.2596 | -7.5908 | 1.2690 | 0.5965 | 0.6077 | 8.1547 |
| Doxorubicin | HCC1395 | -6.2596 | 0.8054 | -5.2156 | -6.2596 | -6.7053 | 0.4539 | 0.0000 | 0.7486 | 8.4055 |
| Doxorubicin | MCF 10A | -6.2596 | 0.9093 | -6.9277 | -6.9278 | -6.9505 | 1.1620 | 0.0000 | 0.1434 | 7.6021 |
| Doxorubicin | HCC3153 | -6.2596 | 0.9648 | -6.5902 | -6.5902 | -6.9511 | 1.0970 | 0.0000 | 0.3026 | 7.7658 |
| Doxorubicin | LY2 | -6.2596 | 0.8251 | -6.3938 | -6.3939 | -6.4425 | 0.9242 | 0.0000 | 0.4291 | 8.0294 |
| Doxorubicin | MX1 | -6.2596 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.1928 |
| Doxorubicin | MCF12A | -6.2596 | 0.8299 | -6.9235 | -6.9235 | -7.4358 | 0.7362 | 0.0000 | 0.2490 | 6.9971 |
| Doxorubicin | SUM52PE | -6.2596 | 0.9158 | -6.3140 | -6.3140 | -6.6296 | 1.3770 | 0.0000 | 0.4570 | 8.0919 |