NPK76-II-72-1 KiNativ -- single dose experiment - Dataset (ID:20106)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
NPK76-II-72-1 HeLa PI42C
TLVIkEVSSEDIADMHSNLSNYHQYIVK
ATP
38.8
 10
uM
NPK76-II-72-1 PC-3 PI42C
TLVIkEVSSEDIADMHSNLSNYHQYIVK
ATP
38.6
 10
uM
NPK76-II-72-1 PC-3 PITSLRE
DLkTSNLLLSHAGILK
Lys2
4.2
 10
uM
NPK76-II-72-1 HeLa PKR
DLkPSNIFLVDTK
Lys2
0.6
 10
uM
NPK76-II-72-1 PC-3 PKR
DLkPSNIFLVDTK
Lys2
-6.6
 10
uM
NPK76-II-72-1 HeLa PRPK
FLSGLELVkQGAEAR
ATP Loop
11.9
 10
uM
NPK76-II-72-1 PC-3 PRPK
FLSGLELVkQGAEAR
ATP Loop
-12.2
 10
uM
NPK76-II-72-1 PC-3 ROCK1,ROCK2
DVkPDNMLLDK
Lys2
20.4
 10
uM
NPK76-II-72-1 HeLa RSK1,RSK2_domain1
DLkPENILLDEEGHIKLTDFGLSK
Lys2
13.6
 10
uM
NPK76-II-72-1 HeLa RSK2_domain1
LTDFGLSkESIDHEKK
Activation Loop
-7.1
 10
uM
NPK76-II-72-1 PC-3 RSK2_domain2
DLkPSNILYVDESGNPESIR
Lys2
28.5
 10
uM
NPK76-II-72-1 HeLa RSK2_domain2
SkRDPTEEIEILLR
Protein Kinase Domain
14.1
 10
uM
NPK76-II-72-1 PC-3 RSK2_domain2
SkRDPTEEIEILLR
Protein Kinase Domain
15.9
 10
uM
NPK76-II-72-1 HeLa RSKL1_domain1
VLGVIDkVLLVMDTR
Protein Kinase Domain
-207.2
 10
uM
NPK76-II-72-1 HeLa SGK3
FYAVkVLQK
Lys1
-8.0
 10
uM
NPK76-II-72-1 HeLa SLK
DLkAGNILFTLDGDIK
Lys2
46.4
 10
uM
NPK76-II-72-1 PC-3 SLK
DLkAGNILFTLDGDIK
Lys2
12.8
 10
uM
NPK76-II-72-1 HeLa SMG1
DTVTIHSVGGTITILPTkTKPK
ATP
-7.2
 10
uM
NPK76-II-72-1 HeLa STLK5
YSVkVLPWLSPEVLQQNLQGYDAK
Activation Loop
69.5
 10
uM
NPK76-II-72-1 HeLa TAO1,TAOK3
DIkAGNILLTEPGQVK
Lys2
-21.1
 10
uM
NPK76-II-72-1 PC-3 TAO1,TAOK3
DIkAGNILLTEPGQVK
Lys2
-2.8
 10
uM
NPK76-II-72-1 PC-3 TAOK2
DVkAGNILLSEPGLVK
Lys2
1.7
 10
uM
NPK76-II-72-1 HeLa TBK1
TGDLFAIkVFNNISFLRPVDVQMR
Lys1
50.3
 10
uM
NPK76-II-72-1 HeLa TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
12.6
 10
uM
NPK76-II-72-1 PC-3 TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
-19.2
 10
uM